Scientists have found longevity biomarkers
Exploring the effects of 17 different lifespan-extending interventions on gene activity, researchers identified genetic biomarkers for longevity in mice. ... Read More...
RNA
Highest-resolution human brain ‘parts list’ to date lays road map to better treatments
Researchers have created the most comprehensive 'parts list' of the human brain to date. They uncovered crucial differences between human and mouse brain cells. The findings may explain why many drugs used in research do not work in human models.... Read More...
Stress in pregnancy impacts childrens’ vulnerability to stress in adulthood
Prenatal stress can have an epigenetic impact on the future mental health of offspring. Adult children of women who experienced prenatal stress are more vulnerable to stress and other mental health disorders. ... Read More...
Study links gene to children with physical and intellectual disabilities
Rare variants in the DDX6 gene have been linked to significant disruption in the development of the central nervous system, affecting basic motor skills and resulting in intellectual disabilities.... Read More...
Exploring genetic ‘dark matter,’ researchers gain new insights into autism and stroke
Study illuminates the role of non-coding mutations in autism spectrum disorder. Researchers say non-coding mutations may also shed light on an array of other neurological and health disorders.... Read More...
Study pinpoints cell types affected in brains of multiple sclerosis patients
Projection neurons have been implicated in the progression of multiple sclerosis. A new study reports projection neurons are damaged by immune cells. This damage could contribute to both atrophy and cognitive changes associated with the disease.... Read More...
Persistent HIV in central nervous system linked to cognitive impairment
HIV can persist in the nervous system, even when the virus is suppressed. Even when the virus is suppressed, neurocognitive problems associated with the infection can persist.... Read More...
Are the ‘viral’ agents of MS, ALS and schizophrenia buried in our genome?
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.... Read More...
Genetic variation linked to response to anxiety could inform personalized therapies
A study of marmoset monkeys reveals a genetic variation of the SLC6A4 repeat region may contribute to anxiety via neurochemical changes in brain areas associated with emotional processing.... Read More...
Gene activity database could spare thousands of mice
A new, comprehensive database of gene activity in mice, which incorporates ten disease models, could significantly reduce the need for animal testing.... Read More...
New research could help predict seizures before they happen
Specific transfer RNAs (tRNAs) are associated with epilepsy. The levels of tRNA fragments in blood samples are higher pre-seizure. The findings provide a novel biomarker for the detection of seizures prior to their occurrence.... Read More...
High levels of rare gut bacteria may be linked to restless legs syndrome
Findings from a small sample study link small intestinal bacterial overgrowth (SIBO) to restless leg syndrome. ... Read More...