The interaction of Tau with RNA is a key stage in the development of Alzheimer's disease and other dementias.
Multiple neurodegenerative disorders harbor similar fundamental dysfunctional cellular processes.
Findings support the theory that microRNAs are essential for the development and evolution of intelligent life.
A novel compound eliminates disease-causing segments of RNA associated with ALS and dementia, and restores the health of neurons in mouse models.
Researchers have identified a blood biomarker that predicts the risk of suicide in patients with major depressive disorder. The biomarker also can help researchers understand the molecular changes in suicide victims.
mRNA decay may facilitate tau-induced damage to the brain and associated apoptosis that contributes to a range of neurodegenerative disorders. Researchers found the mechanism can be altered pharmacologically, providing a new target for the development of therapeutics to prevent or slow the progression of some neurodegenerative disorders.
A new study expands the understanding of how brain cells communicate. Researchers discovered reversing the modification of molecular messages at the synapse may contribute to reversible psychiatric disorders and early-stage neurodegenerative diseases.
Researchers have created an atlas representing changes in the levels of RNA made in different cell types in the ear following noise-induced hearing loss. They also discovered certain FDA-approved medications for diabetes and other disorders may protect against noise-related hearing loss.
BARseq2 is a new technique that allows researchers to trace thousands of brain circuits simultaneously.
Using single nucleus RNA sequencing, researchers have mapped 21 subtypes of motor neurons in the spinal cords of mice.
Study sheds new light on the role noncoded RNAs play at the synapse.
COVID-19 may not directly infect the brain, but the virus is still capable of causing significant neurological damage, a new study reports. Researchers say the neurological changes seen as a result of coronavirus infection are likely related to inflammation triggered by viral infection in different parts of the body or the brain's blood vessels.
