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·February 23, 2021·4 min read

Seasonal Variation in Daylight Influences Brain Function

The seasonal duration of daylight influences the number of opioid receptors in the brain. The findings shed new light on a potential mechanism behind seasonal affective disorder.

Featured Neurology Neuroscience

·February 2, 2021·4 min read

Automated Imaging Detects and Tracks Brain Protein Involved in Alzheimer’s Disease

A new automated method can identify and track the development of tau deposits in the brain. The method could lead to an earlier diagnosis of Alzheimer's disease.

Featured Neurology Neuroscience Videos

·September 22, 2020·6 min read

Parkinson’s Disease Is Not One, but Two Diseases

Parkinson's disease can be divided into two variants that start in different places in the body. For some, the neurodegenerative disease starts in the intestines and spreads to the brain. In others, the disease begins in the brain and spreads to the intestines and other organs.

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Featured Neurology

·July 28, 2020·4 min read

Alzheimer’s Protein in Blood Indicates Early Brain Changes

Blood samples taken from people enrolled in an Alzheimer's research study revealed higher levels of phosphorylated tau 217 that correlated with the presence of amyloid plaques. People with amyloid in their brains had up to three times more of the tau protein in their blood than those who had no evidence of amyloid accumulation. The higher levels of the protein were evident even in people with no signs of cognitive decline.

Featured Neurology

·July 15, 2020·4 min read

Super-Agers Show Resistance to Tau and Amyloid Accumulation

PET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins.

Featured Genetics Neurology

·June 23, 2020·5 min read

New gene may drive earliest brain changes in Alzheimer’s

Genetic analysis of almost 4,300 samples reveals a link between the appearance of amyloid deposits, APOE, and a novel gene called RBFOX1. Lower levels of RBFOX1 in the brain appear to be associated with increased amyloid and global cognitive decline over a person's lifetime.

Featured Neuroscience Psychology

·June 16, 2020·2 min read

The molecular mechanisms of depression

Study reveals how the brain's opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain.

Featured Neuroscience Open Neuroscience Articles Psychology

·June 1, 2020·4 min read

How ketamine combats depression

Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.

Featured Neuroscience Open Neuroscience Articles

·April 16, 2020·4 min read

Neuronal and neurotransmitter systems dynamic coupling explains the effects of psilocybin

Computational simulations reveal the integration of both neuronal and neurotransmitter systems at a whole-brain level is vital to fully understand the effects of psilocybin on brain activity.