FeaturedNeurologyNeuroscience·February 17, 2020·4 min readBeta-arrestin-2 increases neurotoxic tau driving frontotemporal dementiaThe protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.Read More
FeaturedGeneticsNeurologyNeuroscience·January 15, 2020·3 min readInflammation a “game changer” as cellular death dance discoveredTNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.Read More
FeaturedNeurology·August 1, 2018·4 min readAlzheimer’s Drug May Stop Disease If Used Before Symptoms AppearResearchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·July 26, 2018·4 min readTraffic Jams in the BrainA new study reports disrupted transportation routes in nerve cells are a significant cause of Parkinson's disease.Read More
FeaturedNeurologyOpen Neuroscience Articles·June 28, 2018·3 min readNew Mechanism to Explain the Spread of Alzheimer’s DiscoveredResearchers report exosomes help neuron-to-neuron growth and the transfer of oligomer amyloid beta, resulting in apoptosis. The study reveals exosomes may be a primary mediator of the pathogenic progression of Alzheimer's disease.Read More
FeaturedNeurology·April 9, 2018·3 min readOverlapping Mechanisms in HIV Cognitive Disorders and Alzheimer’sA new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.Read More
FeaturedNeurology·October 19, 2017·5 min readBinding Sites on Amyloid Beta Peptide DiscoveredResearchers have invented a probe that lights up when it binds to a misfolded amyloid peptide.Read More
FeaturedNeurology·October 11, 2017·4 min readHow Green Tea Extract Could Help Protect Against Alzheimer’sResearchers reveal a compound in green tea extract may help protect the brain against cognitive decline associated with Alzheimer's by coating toxic oligomers.Read More
FeaturedNeurology·December 22, 2016·3 min readPromising Discovery For A Non-Invasive Early Detection of Alzheimer’sA new paper details a technology that can detect pathological oligomeric forms of tau in Alzheimer's patients through human blood platelets.Read More
FeaturedNeurology·November 23, 2016·3 min readNew Imaging Technique Measures Toxicity of Proteins Associated With Alzheimer’s and Parkinson’s DiseasesResearchers have developed a new imaging technique that makes it possible to study why proteins associated with Alzheimer’s and Parkinson’s diseases may go from harmless to toxic.Read More
FeaturedNeurologyNeuroscience Videos·October 3, 2016·6 min readComputer Simulations Explore How Alzheimer’s StartsA new study reports a computer simulation has been able to explore the initial steps of the molecular processes that lead to Alzheimer's disease.Read More
FeaturedNeurology·June 10, 2016·4 min readNew Clues to Toxic Forms of Amyloid Beta in Alzheimer’sResearchers made a subtle alteration to the amyloid beta protein. The change affect its aggregation behavior and stabilizes an intermediate form with enhanced toxicity.Read More