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iPSCs

Featured Genetics Neuroscience Psychology

·December 22, 2022·3 min read

Stem Cells May Help Identify New Schizophrenia Drugs

Researchers identified 20 drug candidates that reduce C4 immune protein secretion from astrocytes. The discovery could pave the way to treating schizophrenia and other disorders associated with C4 dysregulation in astrocytes.

This shows the outline of a head and a brain

Featured Genetics Neuroscience Psychology

·October 21, 2022·6 min read

How Neurons From PTSD Patients React to Stress

Neurons derived from stem cells of combat veterans with PTSD react differently to stress hormones than those derived from veterans without PTSD. The findings shed new light on how genetics can cause some to develop PTSD following a traumatic event.

Featured Genetics Neurology Neuroscience

·September 22, 2022·3 min read

Aged Neurons Generated Directly From Skin More Accurately Model Parkinson’s Disease

Researchers successfully turned skin cells from Parkinson's patients into dopaminergic neurons by introducing a combination of neural-inducing genes into the skin cells.

Featured Genetics Neurology Neuroscience

·May 11, 2022·7 min read

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson's associated destruction of dopaminergic cells.

Autism Featured Neuroscience Open Neuroscience Articles

·August 24, 2020·5 min read

Autistic People’s Nerve Cells Differ Before Birth

Atypical brain development begins at the very earliest stages of brain organization, at the level of individual neurons.

Featured Neurology Open Neuroscience Articles

·August 12, 2020·4 min read

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Human-on-a-chip technology could provide a more valuable clinical-based model for ALS.

Featured Genetics Psychology

·August 5, 2020·4 min read

Allelic Imbalance of Chromatin Openness Is Linked to Neuropsychiatric Disorders

Study finds allele-specific open chromatin variants are likely to be linked to several neuropsychiatric traits and illnesses, including schizophrenia and bipolar disorder.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 15, 2020·5 min read

Group of Genes Have Altered Expression in Autism

Study points to a common gene expression profile, regardless of DNA mutations, applicable to any person on the autism spectrum. The dysregulation occurs in neural progenitor cells. While the genetic cause of ASD may be different between individuals, the behavior of the genes is similar in people with autism, and differ from those who are not on the autism spectrum.

Featured Genetics Neurology Neuroscience

·January 27, 2020·5 min read

Parkinson’s disease may start before birth

10% of patients diagnosed with Parkinson's disease are between the ages of 21 and 50. For those with young-onset Parkinson's disease, researchers report the foundations for the disease may have been apparent before they were born. The study also points to a drug, currently approved to treat precancerous skin growths, that has the potential to reduce elevated levels of alpha-synuclein.

This shows the BBB created on the organ-chip

Featured Neurology Neuroscience

·June 6, 2019·4 min read

Scientists recreate blood-brain barrier defect outside the body

Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips.

Featured Neuroscience Open Neuroscience Articles

·February 13, 2019·5 min read

Uncovering the Evolution of the Brain

Researchers have developed a new technique to study the development of human neurons compared to the neurons of nonhuman primates. The findings shed new light on the evolution of the human brain.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·February 12, 2019·3 min read

New Insight into Genetic Mutations Associated with Autism

Using CRISPR gene editing technology, researchers discover increased activity in neurons deficient in the CNTN5 or EHMT2 genes may cause ASD related characteristics in humans.

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iPSCs

Stem Cells May Help Identify New Schizophrenia Drugs

How Neurons From PTSD Patients React to Stress

Aged Neurons Generated Directly From Skin More Accurately Model Parkinson’s Disease

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Autistic People’s Nerve Cells Differ Before Birth

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Allelic Imbalance of Chromatin Openness Is Linked to Neuropsychiatric Disorders

Group of Genes Have Altered Expression in Autism

Parkinson’s disease may start before birth

Scientists recreate blood-brain barrier defect outside the body

Uncovering the Evolution of the Brain

New Insight into Genetic Mutations Associated with Autism

Wasabi Compound Enhances Memory

Genes Associated with Earlier and Higher Reproduction Linked to Accelerated Aging

Novel Multiple Sclerosis Treatment Shows Promise

Brain’s Response to Crucial Language Hub Removal: New Insights

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