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iPSCs

Featured Genetics Neurology Neuroscience

·May 11, 2022·7 min read

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson's associated destruction of dopaminergic cells.

Autism Featured Neuroscience Open Neuroscience Articles

·August 24, 2020·5 min read

Autistic People’s Nerve Cells Differ Before Birth

Atypical brain development begins at the very earliest stages of brain organization, at the level of individual neurons.

Featured Neurology Neurotech Open Neuroscience Articles

·August 12, 2020·4 min read

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Human-on-a-chip technology could provide a more valuable clinical-based model for ALS.

Featured Genetics Psychology

·August 5, 2020·4 min read

Allelic Imbalance of Chromatin Openness Is Linked to Neuropsychiatric Disorders

Study finds allele-specific open chromatin variants are likely to be linked to several neuropsychiatric traits and illnesses, including schizophrenia and bipolar disorder.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 15, 2020·5 min read

Group of Genes Have Altered Expression in Autism

Study points to a common gene expression profile, regardless of DNA mutations, applicable to any person on the autism spectrum. The dysregulation occurs in neural progenitor cells. While the genetic cause of ASD may be different between individuals, the behavior of the genes is similar in people with autism, and differ from those who are not on the autism spectrum.

Featured Genetics Neurology Neuroscience

·January 27, 2020·5 min read

Parkinson’s disease may start before birth

10% of patients diagnosed with Parkinson's disease are between the ages of 21 and 50. For those with young-onset Parkinson's disease, researchers report the foundations for the disease may have been apparent before they were born. The study also points to a drug, currently approved to treat precancerous skin growths, that has the potential to reduce elevated levels of alpha-synuclein.

This shows the BBB created on the organ-chip

Featured Neurology Neuroscience

·June 6, 2019·4 min read

Scientists recreate blood-brain barrier defect outside the body

Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips.

Featured Neuroscience Open Neuroscience Articles

·February 13, 2019·5 min read

Uncovering the Evolution of the Brain

Researchers have developed a new technique to study the development of human neurons compared to the neurons of nonhuman primates. The findings shed new light on the evolution of the human brain.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·February 12, 2019·3 min read

New Insight into Genetic Mutations Associated with Autism

Using CRISPR gene editing technology, researchers discover increased activity in neurons deficient in the CNTN5 or EHMT2 genes may cause ASD related characteristics in humans.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·December 3, 2018·3 min read

Experimental Cancer Drug Shows Promise for Parkinson’s

Tasquinimod, a new cancer drug, appears to control genes associated with Parkinson's disease, a new study reports.

Featured Neurology Neuroscience Open Neuroscience Articles

·July 26, 2018·4 min read

Traffic Jams in the Brain

A new study reports disrupted transportation routes in nerve cells are a significant cause of Parkinson's disease.

Electrophysiology Featured Genetics Neurology Open Neuroscience Articles

·June 22, 2018·3 min read

New Technique Helps Uncover Changes in ALS Neurons

A new method reveals some ALS affected neurons display hypo-excitability. Researchers say these changes most likely represent early steps in the disease progression.

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