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FTD

Featured Neurology Open Neuroscience Articles

·August 24, 2020·5 min read

Insights Into New Form of Dementia

Study reveals new criteria that could differentiate between FTD and LATE.

Featured Genetics Neurology

·August 20, 2020·5 min read

Autoimmune Diseases in ALS Patients Linked to Genetic Mutation

Study reveals why some people with ALS are prone to developing autoimmune diseases. A genetic mutation that decreases the expression of C9orf72 causes the stimulation of interferon genes (STING) protein to become hyperactive. The hyperactivity leads to increased production of interferons. This can lead to systemic inflammation and the development of autoimmune diseases.

Featured Genetics Neurology Neuroscience

·June 10, 2020·4 min read

New genetic defect linked to ALS

Researchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 17, 2020·5 min read

Inflammation in the brain linked to several forms of dementia

In all three types of frontotemporal dementia, researchers found the more the inflammation in each part of the brain, the more harmful the build-up of junk proteins.

Featured Neurology Neuroscience

·February 17, 2020·4 min read

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 10, 2020·2 min read

Antibiotics could be promising treatment for form of dementia

Gentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia.

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Featured Neurology Neuroscience Open Neuroscience Articles

·January 8, 2020·7 min read

Lifestyle choices could slow familial frontotemporal dementia

Those with a genetic predisposition to frontotemporal dementia (FTD) can become resilient to the neurodegenerative disease by remaining physically and mentally active.

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Featured Neuroscience Open Neuroscience Articles Psychology

·December 5, 2019·4 min read

Rats use same brain area as humans to empathize with others

Reducing activity in the anterior cingulate decreases empathetic responses in rats. The data suggests an observer shares the emotions of others as it enables them to prepare for danger.

Featured Neurology Neuroscience Open Neuroscience Articles

·November 25, 2019·5 min read

Study shows extra virgin olive oil staves off multiple forms of dementia in mice

Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.

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Featured Neurology Neuroscience

·November 20, 2019·4 min read

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 16, 2019·4 min read

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.