Boosting omega-3 fatty acid intake helps to preserve brain health and improve cognition in middle age, a new study reports. For those with the Alzheimer's associated APOE4 gene, omega-3 fatty acid intake was associated with greater hippocampal volume and less small vessel disease.
People with lower EPA and DHA in red blood cell membranes, which correlates to lower scores on the Omega-3 index, were found to have an increased risk of cardiovascular disease and ultimately a decrease in lifespan compared to those who scored higher on the omega-3 index.
Adding a lysophospholipid form of EPA, LPC-EPA, to the diet increased omega 3 fatty acid levels up to 100 fold in the brains of mice, researchers report. The amount required for the boost in Omega 3 levels is less than a milligram a day. In humans, researchers report, the equivalent is less than a quarter of a gram of LPC-EPA per day to have the same effect.