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CSF

·October 29, 2025·8 min read

Your Brain “Zones Out” After Poor Sleep To Clean Itself

New research shows that during moments of lost focus after poor sleep, the brain releases a wave of cerebrospinal fluid (CSF)—the same cleansing process that normally occurs during deep sleep. Using simultaneous EEG and fMRI scans, scientists found that these fluid pulses occur precisely when attention lapses, suggesting the brain is attempting to catch up on missed “housekeeping.”

Featured Neurology Neuroscience

·October 23, 2025·8 min read

Brain’s Waste System Breakdown Linked to Dementia Risk

Researchers have discovered that problems with the brain’s waste-clearing system—the glymphatic system—may significantly raise the risk of developing dementia. In one of the largest studies to date, MRI data from 40,000 adults revealed that impaired cerebrospinal fluid (CSF) flow predicts dementia risk years before symptoms appear.

Featured Neurology Neuroscience

·August 16, 2024·5 min read

Restoring Brain’s Waste-Clearing System Reverses Aging Effects

New research in mice reveals that aging slows the brain's ability to clear out harmful waste, contributing to neurological disorders like Alzheimer's and Parkinson's. Scientists have found that restoring function in the brain's waste-clearing system, known as the glymphatic system, can reverse these age-related effects. Using a clinically approved drug, researchers increased the efficiency of waste removal, offering a potential treatment strategy for age-related brain diseases.

Featured Neuroscience

·January 26, 2024·5 min read

Nasal Lymphatic Network Crucial for Brain CSF Drainage

Researchers discovered a crucial network of lymphatic vessels at the back of the nose, which significantly contributes to draining cerebrospinal fluid (CSF) from the brain. This study reveals a previously unknown CSF outflow route, offering insights into neurodegenerative conditions.

Featured Neuroscience Open Neuroscience Articles

·February 9, 2023·5 min read

Disrupted Flow of Brain Fluid May Underlie Neurodevelopmental Disorders

Cerebral spinal fluid may play a key, underrecognized role in normal brain development and neurodevelopmental disorders.

Featured Neurology Neuroscience

·December 13, 2022·4 min read

New Immune Culprit Discovered in Alzheimer’s Disease

In patients with cognitive decline, the cerebral spinal immune system is dramatically altered. The findings shed light on how inflammation and the immune system play a role in neurodegenerative diseases like Alzheimer's.

Featured Neurology

·July 14, 2020·4 min read

Link Between Delirium and Brain Energy Disruption Discovered

Artificially inducing peripheral inflammation in mice triggered the sudden onset of delirium-like cognitive dysfunction, and this was mediated by a disturbance in energy metabolism.

This shows the CSF in the brain during sleep

Featured Neuroscience

·November 1, 2019·4 min read

Are we ‘brainwashed’ during sleep?

Study reveals as we sleep, cerebrospinal fluid pulses in the brain in rhythmic patterns.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 16, 2019·3 min read

Persistent HIV in central nervous system linked to cognitive impairment

HIV can persist in the nervous system, even when the virus is suppressed. Even when the virus is suppressed, neurocognitive problems associated with the infection can persist.

Featured Genetics Neurology Neuroscience

·July 15, 2019·5 min read

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.