In patients with cognitive decline, the cerebral spinal immune system is dramatically altered. The findings shed light on how inflammation and the immune system play a role in neurodegenerative diseases like Alzheimer's.
Researchers say their findings about immune system changes early in Alzheimer's could lead to new blood tests that may be used to detect the disease before it becomes symptomatic.
A previously unrecognized system that drains waste from the brain at a rapid clip has been discovered by neuroscientists at the University of Rochester Medical Center and dubbed the glymphatic system.
Artificially inducing peripheral inflammation in mice triggered the sudden onset of delirium-like cognitive dysfunction, and this was mediated by a disturbance in energy metabolism.
Boston University School of Medicine researchers have identified several new genes associated with Alzheimer's disease, including some which may cause functional and structural alterations in the brain. The findings could help to shed light on the processes leading up to the development of the neurodegenerative disease.
Study reveals changes in blood flow to different brain areas may be the earliest sign of Alzheimer's disease.
Researchers have discovered an early immune response in people with a genetic predisposition to Alzheimer's disease.
A new study in Nature Communications refutes long standing belief, reporting that cerebrospinal fluid exits the cranial cavity via lymph vessels.
According to a new study, sleeping on your side helps the clear the brain of some neurotoxins, like amyloid beta, and could potentially reduce risk for developing some neurodegenerative disorders.
According to researchers, Alzheimer's disease may be more prevalent in women, not simply because they live longer on average, but due to the APOE E4 gene. Researchers found the APOE association was greater for women in the Tau pathway than in men. However, there was no difference between APOE expression in the amyloid pathway in women compared to men.
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.
Newborns who suffer a brain hemorrhage at birth could be saved from developing hydrocephalus thanks to a new drug which prevents brain swelling, researchers discover.
