M1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.
Sleep deprivation doesn't just alter brain activity, it also changes the connection between neurons. Both changes have a significant effect on working memory and cognitive performance.
Artificial neural networks based on human brain dynamics can outperform current deep learning models in learning capabilities.
Study reveals structural changes of connectivity in the thalamus to other brain areas in those with congenital blindness, providing evidence of brain plasticity. The areas of the thalamus that connect with the occipital lobe in those with blindness are weaker and smaller, giving space to connections in the temporal cortex which are strengthened.
Findings support modern thought that neural networks store information by making short-term alterations to the synapses. The study sheds new light on short-term synaptic plasticity in recent memory storage.
In the olfactory bulb, levels of oxytocin rise and peak when new neurons incorporate themselves into neural networks. The findings shed new light on adult neurogenesis and brain plasticity.
Researchers find significant changes in fathers' brains between the prenatal and the postpartum period. The main changes occurred in cortical areas associated with visual processing, attention, and empathy toward their baby.
Study provides evidence of a critical period for neuroplasticity in the frontal cortex during the teenage years, a time at which risk-taking behaviors and mental illness risk peak.
Hemispherectomy patients who had a hemisphere of their brain removed during childhood can correctly recognize differences between pairs of words or faces 80% of the time, a new study reports. The findings reveal how the brain adapts when it is highly plastic.
In children who experienced a left-hemisphere stroke within days of birth, brain plasticity allows the right hemisphere to acquire language abilities normally handled by the left hemisphere while maintaining its own language ability as well.
A new study reveals how our brain swiftly adapts to compensate for dynamic and abrupt essential changes in behavior.
Researchers discuss how psychedelics can affect the brain and provide therapeutic benefits for those suffering from a range of psychiatric disorders.