MW189, a small molecule drug candidate, blocks abnormal inflammation in the brain which contributes to injury and disease induced neurological impairments. Read More
Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia. Read More
Hyaluronic acid, a substance naturally produced by the human body and a popular additive in cosmetics that boast plumper skin, may be a useful tool in treating neuroinflammation. Read More
Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE. Read More
A new mouse study reveals long term exposure to bacteria associated with periodontal disease causes neuroinflammation and neurodegeneration, leading to similar effects of Alzheimer's disease. Researchers report periodontal disease may be an initiator of Alzheimer's. Read More
Researchers have discovered a direct association between astrocytes and Alzheimer's disease. In a new study, researchers report astrocytes in the brains of Alzheimer's patients produced significantly more amyloid beta than astrocytes in the brains of people without the disease. Read More
Researchers have identified increased inflammatory activation markers in the brains of people with major depressive disorder who report suicidal ideations. The findings support recent research that anti-inflammatories may provide antidepressant effects for some patients. Read More
Brain inflammation is 30% higher in people with OCD than in their peers without the disorder, a new study reports. Read More
Findings could help guide researchers to develop new drugs to treat Multiple Sclerosis and other neurological diseases. Read More
A new study reports neuroinflammation could have a direct involvement in the development of CTE. Read More
Researchers discover a link between gut bacteria and brain inflammation in patients with cirrhosis. Read More
A new study reports air evacuations may pose a significant added risk for people with TBI as they could potentially cause more damage. Read More
