Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.
A new study reports air evacuations may pose a significant added risk for people with TBI as they could potentially cause more damage.
Researchers have discovered a direct association between astrocytes and Alzheimer's disease. In a new study, researchers report astrocytes in the brains of Alzheimer's patients produced significantly more amyloid beta than astrocytes in the brains of people without the disease.
A new gene expression study of the brains of those with autism is the largest of its kind.
Researchers have identified increased inflammatory activation markers in the brains of people with major depressive disorder who report suicidal ideations. The findings support recent research that anti-inflammatories may provide antidepressant effects for some patients.
A new study reports neuroinflammation could have a direct involvement in the development of CTE.
COVID-19 can spark a severe immune response in the central nervous system, affecting immune cells in the vascular system and brain.
A 14-year-old boy’s turnaround and quick recovery after being stricken by encephalitis - which led to him being hospitalized for six weeks and put into a medically induced coma after falling critically ill - shows that the newest generation of DNA analysis tools can be harnessed to reveal the cause of a life-threatening infection even when physicians have no suspects.
MW189, a small molecule drug candidate, blocks abnormal inflammation in the brain which contributes to injury and disease induced neurological impairments.
Researchers have identified an exceptional mouse model of schizophrenia. The study identified a mutant mouse lacking the Schnurri-2 protein (Shn-2 KO) that exhibits behavioral deficits and other brain features consistent with schizophrenia.