A new study supports p38α MAPK as a possible clinical target for treating central nervous system disorders associated with uncontrolled brain inflammation, including TBI.
Inflammation in the brain prevents cells from accessing the iron they need in order to perform a critical role in neurodevelopment.
New research reports galactic cosmic rays cause significant damage to the central nervous system and results in cognitive impairments for astronauts on extended space flights.
Mainly associated with COVID infection in the elderly, researchers report a young, otherwise healthy woman was diagnosed with COVID-19 CNS vasculitis following infection.
Researchers discover a link between gut bacteria and brain inflammation in patients with cirrhosis.
A 14-year-old boy’s turnaround and quick recovery after being stricken by encephalitis - which led to him being hospitalized for six weeks and put into a medically induced coma after falling critically ill - shows that the newest generation of DNA analysis tools can be harnessed to reveal the cause of a life-threatening infection even when physicians have no suspects.
Researchers have identified increased inflammatory activation markers in the brains of people with major depressive disorder who report suicidal ideations. The findings support recent research that anti-inflammatories may provide antidepressant effects for some patients.
Researchers have identified an exceptional mouse model of schizophrenia. The study identified a mutant mouse lacking the Schnurri-2 protein (Shn-2 KO) that exhibits behavioral deficits and other brain features consistent with schizophrenia.
Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.
A new study suggest IVIg plays a key role in the reduction of amyloid deposition.
A new gene expression study of the brains of those with autism is the largest of its kind.