Researchers have identified a pathway involving a protein called Rab35 in glioblastoma brain cancer. The study reports restoring the activity of Rab35 could have therapeutic benefits for those with glioblastoma. Read More
20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial. Read More
Anticoagulant drugs that inhibit thrombin were shown to reduce the number of brain metastases in mouse models. Read More
Heating up cancer cells as they are being targeted with chemotherapy appears to be a highly effective way of killing them off. Read More
Study reports brain tumors may arise when damaged brain tissue does not heal correctly. Researchers say some glioblastoma form when the normal healing process gets derailed by mutations. This process could begin many years before patients become symptomatic of brain cancer. Read More
Loperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells. Read More
Researchers have identified a cancer-causing mutation in the PDGFRA gene that drives cell mutation and growth when activated. The findings have implications for the treatment of a subset of glioblastoma brain cancer. Read More
Reductive stress promotes protein aggregation in neuroblastoma cells and impairs neurogenesis. Read More
Increased YTHDF3 expression appears to be a key driver in brain metastases. Read More
Myeloid cells can suppress the immune response, allowing breast cancer cells to metastasize in the brain and form secondary tumor sites. Read More
MP-Pt(IV), a second generation prodrug appears to have curative properties against glioblastoma when coupled with chemotherapy in mouse models. Read More
Study reveals how two key molecules, Rab27b, and epiregulin, interact to contribute to radioresistance in glioblastoma brain cancer. Read More