Study describes how the loss of the SMARCB1 gene negatively impacts neural development and promotes tumor growth in ATRT, a rare and fast-progressing form of pediatric brain cancer. Read More
A small molecular compound has been discovered that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma brain cancer, making tumors more responsive to therapies. Read More
Experimental drugs designed to reduce the body's natural production of alpha-ketoglutarate slow tumor growth and increase lifespan in mouse models of DIPG. Read More
Mouse study reveals the deletion of the OSMR gene significantly improves glioblastoma tumor response to therapy and extended lifespan. Read More
Glioblastoma brain cancer cells that are more resistant to radiation therapy have higher levels of purines. Reducing the level of purines made the cancer cells more sensitive to radiation. Read More
Glioblastoma brain cancer originates from a pool of stem cells that can be a significant distance away from where the tumor eventually forms. Read More
Researchers have identified specific characteristics of vestibular schwannomas in children. While children have similar symptoms of the brain tumors as experienced by adults, the tumor size was typically larger in pediatric patients at the time of diagnosis. Read More
An oncogene believed to be responsible for glioblastoma brain cancer has been identified. AVIL, a gene that normally helps cells to maintain their shape and size, can shift into overdrive, causing cancer cells to form and spread. Blocking the gene's activity completely destroyed glioblastoma cancer cells in mouse models, but did not have any effect on healthy cells. The findings provide potential new treatment avenues for the deadly brain cancer. Read More
Focused ultrasound treatments show promise in the fight against glioblastoma brain cancer. Sonodynamic therapy may also help treat other difficult-to-treat cancers. Read More
Cancer itself, rather than chemotherapy alone, may contribute to the development of neuropathy some patients experience. Read More
Trifluoperazine, a dopamine receptor antagonist commonly prescribed for schizophrenia, used in combination with radiation therapy delays the growth of glioblastoma brain tumors and prolongs survival for brain cancer. Read More
Neurons and immune cells work together to promote tumor growth in neurofibromatosis type 1. Read More
