Researchers study the effect of letrozole , a drug designed for the treatment of breast cancer in postmenopausal women, on glioblastoma brain cancer.
Using gene editing to boost the production of SOD3 in the choroid plexus reduced oxidative damage to brain tissue and cerebral spinal fluid in mice exposed to methotrexate.
Researchers have uncovered the molecular mechanisms behind cognitive deficits and brain fog associated with chemotherapy, and identified a current FDA-approved drug for multiple sclerosis that can help reduce chemotherapy-induced cognitive impairments.
A new method that targets the astrocytes surrounding glioblastoma brain cancer eradicates tumor cells and extends lifespan in animal models.
Exposure to chemicals such as melamine, cyanuric acid, and aromatic amines from household products, hair dyes, and pesticides can cause cancer and lead to child developmental issues, researchers report. The study found the majority of pregnant women have levels of the toxic chemicals in urine samples.
Neurofeedback has the potential to alleviate symptoms of "brain fog" and cognitive impairments associated with chemotherapy.
In response to treatment, high-grade gliomas remodel the surrounding brain environment, creating interactions with nearby neurons and immune cells in ways that protect tumor cells and protect them from the body's natural defense.
Dementia patients with a history of cancer demonstrate better cognition at dementia diagnosis than their peers with no history of cancer.
Researchers found a positive correlation between glioblastoma cell proliferation and lactate metabolic indicators. Based on this observation, the researchers developed a biomimetic formulation using targeted delivery agents for lactate metabolism-based synergistic therapy against glioblastoma brain cancer.
Eliminating Collagen 1 production in tumor cells allowed animal models of brain tumors to live longer.
Infiltrating gliomas are shaped by their genetic evolution and microenvironment, researchers report. The findings may help in the development of therapies to treat glioma brain tumors.
Researchers say the gut microbiome may be a viable targetable biomarker to improve immunotherapy responses in those with glioblastoma and a range of other cancers.
