Artificial nose identifies malignant tissue in brain tumors during surgery
Researchers have developed a new method, using diathermy smoke, to distinguish between malignant tumor tissue and healthy tissue during surgery. ... Read More...
Brain Cancer
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
Immune cells determine how fast certain tumors grow
Immune cells can accelerate the growth of cancerous tumors in mouse models of NF1.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
Natural Compound Found in Broccoli Reawakens the Function of Potent Tumor Suppressor
Targeting the gene WWP1 with indole-3-carbinol, a compound found in broccoli and other cruciferous vegetables, suppressed tumor growth in animal models of cancer.... Read More...
Mutations Synergize in Pediatric Brain Cancer
The epigenetic histone mutation H3.1K27M works in combination with ACVR1 mutations to cause diffuse intrinsic pontine glioma tumors to form and grow quickly.... Read More...
New brain tumor imaging technique uses protein found in scorpion venom
A synthetic, non-toxic form of scorpion venom helps illuminate brain tumors when stimulated by a near-infrared laser. A clinical trial of the agent showed it to be safe for use in brain cancer patients.... Read More...
New technique may improve detection and treatment of advanced brain cancer
Researchers discovered changes in thousands of genes induced by the tumor microenvironment. The study may help in identifying new biomarkers for the early detection, and subsequent treatment, of brain cancers.... Read More...
Proteins stand up to nerve cell regression
Study reveals the critical and novel roles Integrator complex proteins play in promoting healthy brain development in flies. ... Read More...
Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment
Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.... Read More...
Shutting down deadly pediatric brain cancer at its earliest moments
Dysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.... Read More...
New hope for treating childhood brain cancer
DIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.... Read More...