Chronic pain in mice activates Tiam1 in pyramidal neurons in the anterior cingulate cortex, increasing the number of dendritic spines and inducing synaptic plasticity. Ketamine's antidepressant effect in chronic pain is mediated by the drug blocking Tiam1-dependent maladaptive synaptic plasticity in ACC neurons.
Female mice who have not been pregnant or given birth show activation in the anterior cingulate cortex when they acquire maternal behaviors after exposure to pups. The findings reveal through repeated exposure to pups, virgin female mice are capable of learning maternal behaviors that resemble those of mothers following birth.
The anterior cingulate cortex gyrus plays a critical role in our decision to put physical effort into helping out other people.
Researchers reveal how the anterior cingulate cortex and motor cortex collaborate to update behaviors when adding a new step to an established task.
Exposure to the opioid fentanyl induces autism-like behaviors in mice by activating mu-opioid receptors in the anterior cingulate cortex.
The anterior cingulate cortex generates a reactive alarm, increasing its activity to signal to the dorsolateral prefrontal cortex to stop intrusive thoughts and memories.
Study shows chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory brain networks. The findings strengthen the link between type 2 diabetes and Alzheimer's disease.
Heightened states of arousal altered neural circuits in a brain area associated with decision making, resulting in some neurons changing from decision making to internal state monitors.
Switching off activity in the anterior cingulate cortex prevented marmoset monkeys from making an association between behavior and a particular outcome.
Study reveals specific neurons in the ventrolateral prefrontal cortex and anterior cingulate cortex that become active when people are faced with the decision to learn or hide from information about an adverse event the person is not able to prevent.