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AMPK

·April 5, 2023·3 min read

How to Prevent a High-Fat Diet From Throwing Metabolism Out of Whack

Eliminating SAPS3 from the genome of mice allowed the AMPK protein complex to activate and maintain normal energy balance, even with high-fat meals. This discovery could pave the way for developing a new approach to metabolic disorders such as obesity, diabetes, and fatty liver disease.

Electrophysiology Featured Neuroscience

·October 5, 2020·3 min read

How the Brain May Fuel Intense Neural Communication

The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.

Featured Genetics

·August 14, 2020·7 min read

Loss of a Specific Enzyme Boosts Fat Metabolism and Exercise Endurance

The enzyme PHD3 plays a critical role in sensing nutrient availability and regulating the ability of muscles to break down fat. Blocking PHD3 production in mice leads to dramatic improvements in specific measures of fitness. Findings shed light on the key mechanism for how cells metabolize fuel and provide a novel understanding of muscle function and fitness.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 11, 2020·6 min read

Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

A new 3D human gut organoid reveals the molecular system that keeps the intestinal linings sealed and how dysfunction can occur. Findings reveal the diabetes drug metformin can help strengthen the intestinal lining.

This shows two people walking in the evening

Featured Neuroscience Open Neuroscience Articles

·April 18, 2019·6 min read

Two studies explore whether time of day can affect the body’s response to exercise

Two new studies report the time of day is a major modifier of exercise capacity, amplifying the impact exercise has on metabolic pathways and energy homeostasis. Evening exercise, researchers report, has the most productive effect.

Brain Cancer Featured Genetics Neurology

·May 26, 2017·5 min read

Enzyme That Allows Brain Tumor Growth Discovered

A new study reveals how the ACSS2 enzyme allows brain tumors to grow in a nutrient starved environment.

Featured Neurology Open Neuroscience Articles

·January 17, 2017·4 min read

Blocking Neuron Signaling Pathway May Lead to New Treatments For Peripheral Neuropathy

Researchers have identified a signaling pathway that promotes sensory neuron grown and prevents peripheral neuropathy when blocked.

Diagram of how the enzyme controls appetite.

Featured Neuroscience

·October 4, 2016·4 min read

How The Brain Controls Our Appetite

A new study reports researchers have discovered the mechanism behind the enzyme that controls our appetite in response to low glucose availability.

Image shows dendritic spines on a neuron.

Featured Neuroscience

·July 6, 2016·6 min read

Hunger Neurons Are Regulated by a Protein Activated During Fasting

Researchers discover a control mechanism for neurons involved in hunger and eating disorders.

Featured Neurology

·June 26, 2016·3 min read

Combination Therapy May Hold The Key to Slowing Down Alzheimer’s

A new study reports reveratrol could be a therapeutic candidate for the management and treatment of Alzheimer's disease.

Featured Neuroscience

·May 16, 2016·4 min read

Converting Cells to Burn, Not Store, Fat: Mouse Study

Findings could help to find treatments for fight obesity, diabetes and cardiovascular disease, researchers report.

Image shows neurons and a red pecil drawing the outline of a head.

Featured Neurology

·March 10, 2016·4 min read

How Restricting Calorie Intake May Help Protect Against Parkinson’s

Researchers report decreasing caloric intake boosts Ghrlein production, which appears to protects against the hallmarks of Parkinson's disease from developing.

AMPK

How to Prevent a High-Fat Diet From Throwing Metabolism Out of Whack

How the Brain May Fuel Intense Neural Communication

Loss of a Specific Enzyme Boosts Fat Metabolism and Exercise Endurance

Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

Two studies explore whether time of day can affect the body’s response to exercise

Enzyme That Allows Brain Tumor Growth Discovered

Blocking Neuron Signaling Pathway May Lead to New Treatments For Peripheral Neuropathy

How The Brain Controls Our Appetite

Hunger Neurons Are Regulated by a Protein Activated During Fasting

Combination Therapy May Hold The Key to Slowing Down Alzheimer’s

Converting Cells to Burn, Not Store, Fat: Mouse Study

How Restricting Calorie Intake May Help Protect Against Parkinson’s

Untangling the Human Mind: The Interplay Between Cognition and Personality

Empathy’s Influence on Drinking Patterns

Sleep Apnea and Its Link to Alzheimer’s Associated Brain Changes

Getting the Skinny on Cannabis Use: The Effect of Cannabis on Weight and Metabolism

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