The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
The enzyme PHD3 plays a critical role in sensing nutrient availability and regulating the ability of muscles to break down fat. Blocking PHD3 production in mice leads to dramatic improvements in specific measures of fitness. Findings shed light on the key mechanism for how cells metabolize fuel and provide a novel understanding of muscle function and fitness.
A new 3D human gut organoid reveals the molecular system that keeps the intestinal linings sealed and how dysfunction can occur. Findings reveal the diabetes drug metformin can help strengthen the intestinal lining.
Two new studies report the time of day is a major modifier of exercise capacity, amplifying the impact exercise has on metabolic pathways and energy homeostasis. Evening exercise, researchers report, has the most productive effect.
Researchers have identified a signaling pathway that promotes sensory neuron grown and prevents peripheral neuropathy when blocked.
Researchers discover a control mechanism for neurons involved in hunger and eating disorders.
A new study reports reveratrol could be a therapeutic candidate for the management and treatment of Alzheimer's disease.
Findings could help to find treatments for fight obesity, diabetes and cardiovascular disease, researchers report.
Researchers report decreasing caloric intake boosts Ghrlein production, which appears to protects against the hallmarks of Parkinson's disease from developing.