The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
The enzyme PHD3 plays a critical role in sensing nutrient availability and regulating the ability of muscles to break down fat. Blocking PHD3 production in mice leads to dramatic improvements in specific measures of fitness. Findings shed light on the key mechanism for how cells metabolize fuel and provide a novel understanding of muscle function and fitness.
A new 3D human gut organoid reveals the molecular system that keeps the intestinal linings sealed and how dysfunction can occur. Findings reveal the diabetes drug metformin can help strengthen the intestinal lining.
Two new studies report the time of day is a major modifier of exercise capacity, amplifying the impact exercise has on metabolic pathways and energy homeostasis. Evening exercise, researchers report, has the most productive effect.
A new study reveals how the ACSS2 enzyme allows brain tumors to grow in a nutrient starved environment.
Researchers have identified a signaling pathway that promotes sensory neuron grown and prevents peripheral neuropathy when blocked.
A new study reports researchers have discovered the mechanism behind the enzyme that controls our appetite in response to low glucose availability.
Researchers discover a control mechanism for neurons involved in hunger and eating disorders.
A new study reports reveratrol could be a therapeutic candidate for the management and treatment of Alzheimer's disease.
Findings could help to find treatments for fight obesity, diabetes and cardiovascular disease, researchers report.
Researchers report decreasing caloric intake boosts Ghrlein production, which appears to protects against the hallmarks of Parkinson's disease from developing.
