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AgRP neurons

·February 17, 2026·8 min read

Brain’s Developmental Switch May Shape Lifelong Obesity Risk

Is your weight gain pre-programmed? Scientists have discovered a developmental "fate-switch" in the brain that decides if you’ll be driven by hunger or fullness.

Featured Neuroscience

·March 24, 2023·3 min read

Synaptic Plasticity May Affect Diet Outcomes

When dieting, hunger-mediating AgRP neurons receive stronger signals, inducing synaptic plasticity. This may explain why people tend to eat more after a diet and regain the weight they have lost.

Featured Neuroscience Psychology

·July 31, 2022·5 min read

Cells That Control Hunger Affect Brain Structure and Function

AgRP neurons in the hypothalamus play a critical role in shaping the structure and function of the prefrontal cortex in mice. The findings shed light on how the prefrontal cortex is altered in disorders such as schizophrenia.

Featured Neuroscience

·June 27, 2022·4 min read

How the Liver Can Control the Brain and Behavior

The liver appears to play a significant role in regulating feeding behaviors in mice.

Featured Neuroscience

·July 18, 2021·5 min read

How Hunger Boosts Learning About Food in Mice

The findings of a new study in mice may shed light on why dieting humans have a hard time sticking to food restrictions.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 7, 2020·8 min read

The Brain Can Induce Diabetes Remission in Rodents, but How?

Researchers demonstrate how a single injection of fibroblast growth factor 1 (FGF1) can restore blood sugar levels to normal for extended periods in rodent models of type 2 diabetes. Studies show how FGF1 affects specific neurons and perineuronal nets to help restore blood sugar levels to normal, thus sending diabetes into remission.

This shows a mouse and a diagram of a mouse brain

Featured Neuroscience

·July 4, 2019·5 min read

Unraveling the brain’s reward circuits

Study reveals how ArGP and dopamine neurons are linked, and how food and drugs affect them differently. The findings offer clues for the development of new treatments for obesity and substance use disorders.