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Yale

·December 29, 2025·8 min read

Missing Brain Receptor May Hold the Key to Autism

Autistic adults show reduced availability of a key glutamate receptor, mGlu5, across widespread brain regions. This difference supports the theory that an imbalance between excitatory and inhibitory signaling may contribute to autism-related traits.

Autism Featured Neuroscience

·October 4, 2025·6 min read

Born to Connect: Newborn Brain Already Wired for Social Awareness

A new study reveals that the brain’s social perception pathway—a network that processes faces, gaze, and speech—is already active at birth or shortly thereafter. Using advanced imaging data, researchers showed that newborns exhibit robust connectivity in regions responsible for visual and social processing.

Featured Genetics Neuroscience

·August 20, 2025·5 min read

AI Tool Shows Exactly When Genes Turn On and Off

Researchers have developed an AI-powered tool called chronODE that models how genes turn on and off during brain development. By combining mathematics, machine learning, and genomic data, the method identifies exact “switching points” that determine when genes reach maximum activity.

Featured Genetics Neuroscience

·July 17, 2025·4 min read

Neurons Store Backup Energy to Power the Brain Under Stress

New research has uncovered that neurons store their own glycogen, acting as “backup batteries” to keep the brain functioning during energy stress. Using worms and advanced biosensors, scientists found that neurons can tap into glycogen reserves, especially when oxygen or mitochondrial function is limited.

Featured Neurology Neuroscience

·July 14, 2025·8 min read

Why Women Face Higher Alzheimer’s Risk

Women are nearly twice as likely as men to develop Alzheimer’s disease, a disparity that can’t be fully explained by longevity alone. Researchers are exploring biological differences, focusing on X chromosome-linked genes and hormonal shifts like menopause.

Featured Neuroscience Visual Neuroscience

·July 11, 2025·5 min read

Inverse Graphics: How Your Brain Turns 2D Into 3D

Researchers have uncovered how primate brains transform flat, 2D visual inputs into rich, 3D mental representations of objects. This process, dubbed “inverse graphics,” works by reversing the principles of computer graphics — starting from a 2D view, through an intermediate stage, to a 3D model.

Featured Neuroscience

·July 8, 2025·7 min read

One Neuron, Two Behaviors

New research shows a single neuron in fruit flies can trigger two distinct behaviors in response to the same smell. When detecting rotting fruit, one downstream pathway drives the flies toward the source, while another pathway controls their walking speed.

Featured Neurology Neuroscience

·June 30, 2025·6 min read

Alzheimer’s May Disrupt Nerve Insulation Without Reducing Myelin

New research reveals that Alzheimer's disease may impair nerve function not by reducing myelin, but by altering the proteins at the critical interface between axons and their myelin sheath. Scientists found structural abnormalities in the paranode region, where myelin attaches to axons, including clogged nutrient channels and protein buildup that could block signal transmission.

Featured Neuroscience

·June 27, 2025·6 min read

How the Brain Filters Distractions to Stay Focused on a Goal

A new attention model reveals how the human brain allocates limited perceptual resources to focus on goal-relevant information in dynamic environments. Researchers developed “adaptive computation,” a system that prioritizes important visual details—like traffic signals over flashy cars—based on task relevance.

Featured Neuroscience Psychology

·June 21, 2025·6 min read

How PTSD Disrupts Brain Cell Communication

A new study has examined brains affected by PTSD at the single-cell level, uncovering distinct genetic alterations that may drive the disorder. Researchers focused on the dorsolateral prefrontal cortex, a brain region tied to emotional regulation, analyzing individual cell nuclei to map communication differences across PTSD, major depression, and control brains. They found impaired signaling in inhibitory neurons in PTSD, potentially explaining hyperarousal symptoms, and opposing patterns of microglial activity in PTSD versus depression. Vascular endothelial cells in PTSD brains also showed signs of dysfunction, possibly increasing stress hormone exposure.

Featured Neuroscience

·June 1, 2025·7 min read

T Cells Found Living in Healthy Brains

Contrary to long-standing beliefs, T cells—key immune cells—have been discovered in the healthy brains of both mice and humans. These cells, previously thought to only enter the brain during disease, were most concentrated in a region that regulates hunger and thirst.

Featured Neuroscience

·May 15, 2025·4 min read

All Senses Activate Deep Brain Hubs for Focus and Consciousness

A new study reveals that all human senses—sight, hearing, taste, and touch—activate the same deep brain regions linked to consciousness when attention is sharply focused. Using fMRI data from over 1,500 healthy participants, researchers found that sensory input, regardless of the type, engages the midbrain reticular formation and central thalamus. These areas are crucial for regulating alertness, attention, and awareness.