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          psilocybin

          This shows a brain and mushrooms.
          FeaturedNeurologyNeurosciencePainPsychology
          ·October 2, 2025·6 min read

          Psilocybin Rewire Brain Circuits Tied to Pain and Mood

          New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site of injury. In mouse studies, a single dose provided pain relief and mood benefits lasting nearly two weeks by targeting the anterior cingulate cortex.
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          This shows a mom and child with a swirly background.
          FeaturedNeurosciencePsychology
          ·September 30, 2025·7 min read

          Psilocybin Worsens Postpartum Depression Symptoms

          New research shows psilocybin, often studied as a treatment for mental health disorders, may worsen symptoms of postpartum depression in mice. Mothers given the drug showed more anxiety, avoidance of their pups, and lasting depressive-like behaviors.
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          This shows neurons.
          FeaturedNeurosciencePsychology
          ·July 19, 2025·6 min read

          More Than Serotonin: How Psychedelics Engage the Whole Brain

          Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new study reveals their effects go far beyond. Researchers profiled 41 psychedelics against over 300 human receptors and found potent activity at serotonin, dopamine, and adrenergic sites.
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          This shows a psychedelic brain and mushrooms.
          FeaturedNeuroscience
          ·July 9, 2025·4 min read

          Psilocybin Shows Promise as Anti-Aging Therapy

          Psilocybin, the active compound derived from psychedelic mushrooms, significantly delayed cellular aging and extended lifespan in a preclinical study. Researchers observed a 50% increase in the lifespan of human skin and lung cells and a 30% increase in survival in aged mice treated with psilocybin.
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          This shows a person in a church.
          FeaturedNeurosciencePsychology
          ·June 10, 2025·4 min read

          Psilocybin Elevates Spiritual Awareness

          Psilocybin significantly enhances psychological well-being and spiritual insight among clergy members across major world religions. Participants reported lasting positive changes in religious practice, personal beliefs, and vocational effectiveness after two guided psilocybin sessions.
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          This shows a person sitting and mushrooms.
          FeaturedNeurologyNeuroscience
          ·April 30, 2025·6 min read

          Psilocybin Shows Promise for Parkinson’s Mood and Motor Symptoms

          A new pilot study reveals that psilocybin—the compound found in psychedelic mushrooms—may significantly improve mood, cognition, and motor function in people with Parkinson’s disease. The compound was well tolerated, with only mild side effects, and benefits persisted for weeks after dosing. While the study was primarily designed to test safety, researchers observed meaningful and lasting improvements in multiple symptoms.
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          This shows people and mushrooms.
          FeaturedNeurosciencePsychology
          ·April 22, 2025·4 min read

          More People Turning to Psilocybin for Self-Treatment

          Psilocybin use in the U.S. has risen sharply across all age groups since 2019, coinciding with increasing legalization and interest in its therapeutic potential. A new study reveals a 44% rise in past-year use among young adults and a 188% increase among those over 30.
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          This shows a woman and mushrooms.
          FeaturedNeurosciencePsychology
          ·April 4, 2025·3 min read

          How Psilocybin Lifts Mood Without the Hallucinogenic Trip

          Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.
          Read More
          This shows a happy person surrounded by psychedelic swirls.
          FeaturedNeurosciencePsychology
          ·October 8, 2024·3 min read

          Optimism Boosted by Psilocybin, Hinting at Depression Relief

          Researchers have discovered that psilocybin, a psychedelic compound in magic mushrooms, increases optimism and motivation in rats, suggesting potential therapeutic benefits for treating depression. Using computational modeling, scientists observed that rats given psilocybin were more likely to engage in reward-based tasks, indicating enhanced optimism.
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          This shows a woman looking in a mirror.
          FeaturedNeurosciencePsychology
          ·September 24, 2024·2 min read

          Psilocybin Shows Promise in Treating Body Dysmorphic Disorder

          A new study reveals that psilocybin, the active compound in magic mushrooms, may help treat body dysmorphic disorder (BDD) by altering brain connectivity. In a pilot trial, patients with BDD showed significant improvements in symptoms after a single dose of psilocybin, with brain scans indicating increased neural flexibility. Though preliminary, the study suggests that psilocybin could offer new hope for BDD sufferers. Larger studies are needed to confirm its efficacy.
          Read More
          This shows a head and psychedelic swirls.
          FeaturedNeurosciencePsychology
          ·September 22, 2024·7 min read

          Psilocybin Shows Greater Long-Term Benefits Over SSRI for Depression

          A study comparing psilocybin to the SSRI escitalopram found both drugs improved depressive symptoms similarly over six months, but psilocybin offered additional psychosocial benefits. Patients taking psilocybin reported a greater sense of meaning, psychological connectedness, and improved social functioning. These results suggest psilocybin could provide a more holistic treatment option for depression, addressing both symptoms and overall well-being. While promising, psilocybin remains experimental and is only administered in controlled environments.
          Read More
          This shows a woman.
          FeaturedNeurosciencePsychology
          ·August 21, 2024·3 min read

          High-Dose Psilocybin Shows Potential as an Antidepressant Treatment

          A meta-analysis suggests that high doses of psilocybin may alleviate depressive symptoms similarly to the SSRI drug escitalopram. While the effect size was small, psilocybin outperformed placebo in clinical trials, though study design flaws could have led to overestimated results. The findings indicate that psilocybin, particularly in high doses, may offer a new avenue for treating depression, comparable to existing antidepressants.
          Read More
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          This shows a brain.

          Low Choline Could Be a Hidden Driver of Anxiety

          This shows a baby looking at a screen and sound waves.

          Babies’ Brains Tune In to Mom’s Voice and Shift How They See New Faces

          This shows a man holding a wine glass against a psychedelic backdrop.

          Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

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          Why Alzheimer’s Patients Forget Loved Ones

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