Researchers discovered that the orientation of a single amino acid in a sea slug can determine which neuron receptor is activated, leading to different types of neuronal activities. This finding sheds light on how the brain can regulate communication between cells in different ways.
The Blue Brain Project has released a new and enriched 3D digital cell atlas containing more neuron types than the previous version.
Researchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.
Connectomics researchers aim to map and understand how individual neurons connect to each other to form functional networks.
The SLK protein plays a key role in neuron excitability and sensitivity, researchers report.
New findings about neural activity in the sensorimotor cortex may aid in the development of neuroprosthetics to help compensate for neuronal dysfunctions.
Kinase enzymes are essential for neurons to perform autophagy. Researchers found deleting genes that encode kinase NDR1 and NDR2 impairs neuron health and spurs neurodegeneration in both young and old mice.
The autism-linked Gabrb3 gene appears to shape the formation of both normal and atypical neural connections in the brain.
Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer's.
A new 3D electrode array allows researchers to map the activity and location of up to 1 million synaptic links in a living brain.
Researchers have developed a new method to create glutamatergic neuronal cells from SH-SY5Y cells without the use of animal-derived components. The new technique repurposes the B-27 growth supplement. This is the first time SH-SY5Y cells have been transformed into glutamatergic neuronal cells, researchers report.
Brain cells grown in a petri dish can perform goal-directed tasks, such as learning to play a game of Pong.