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myelin

·May 25, 2023·6 min read

Loosely Wrapped Myelin Marks Early Stages of Multiple Sclerosis, Even Before Inflammation

Structural abnormalities in white matter, even before the onset of inflammation, may serve as a new therapeutic target for multiple sclerosis (MS). The study, focusing on 'normal-appearing white matter', identified early changes in myelin, an insulating substance around nerve fibers.

Featured Neurology Neuroscience

·January 5, 2023·5 min read

Intestinal Bacteria May Be an Important Piece in the Jigsaw Puzzle of Multiple Sclerosis

Study reveals differences in the composition and functionality of intestinal bacteria of multiple sclerosis patients depending on whether their illness is active or whether they are in treatment.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 20, 2022·4 min read

Myelin Determines Energy Metabolism in Inhibitory Brain Cells

In PV cells, axons with myelin contain more mitochondria. When myelin is decreased in PV cells, mitochondria also decrease. However, mitochondria increase when myelin is lost in excitatory cells.

Featured Neurology Neuroscience

·December 6, 2022·5 min read

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.

Featured Neuroscience

·December 2, 2022·3 min read

New Drug a Hopeful Advance for Incurable Neurodegenerative Myelin Diseases

Riluzole, an FDA-approved drug to treat ALS, can, in part, correct the molecular cause of some leukodystrophies.

This shows tissue samples from the study

Featured Genetics Neurology Neuroscience

·November 16, 2022·7 min read

Alzheimer’s Risk Gene Undermines Insulation of Brain’s ‘Wiring’

When people carry the Alzheimer's associated APOE4 gene, oligodendrocytes fail to transport fatty molecules to wrap neurons that make brain circuitry connections. This deficit of myelin may contribute to the pathology and symptoms of Alzheimer's disease.

Featured Neurology Neuroscience

·October 26, 2022·3 min read

New Method for Measuring Brain Activity Could Help Multiple Sclerosis Patients

Researchers have developed a new method to measure the delay of neurotransmission in those with multiple sclerosis that does not involve direct stimulation but instead used neural avalanches, or bursts of activity in cascades that spontaneously travel across the brain.

Featured Neuroscience Open Neuroscience Articles

·September 27, 2022·3 min read

Language Learning Difficulties in Children Linked to Brain Differences

Children with developmental language disorder have less myelin in parts of the brain associated with acquiring rules and habits, as well as brain areas associated with language production and comprehension.

Featured Neuroscience

·September 24, 2022·5 min read

Why Our Brain Wiring’s Insulation Matters

Myelin is more complex and dynamic than previously believed.

This shows the outline of a body and sparkling dots over the brain area

Featured Neurology Neuroscience Open Neuroscience Articles

·May 31, 2022·4 min read

Signal Detection Theory May Be Useful for Characterizing Cognitive Fatigue in Multiple Sclerosis

Study reveals an association between signal detection theory, brain activation patterns, and subjective state fatigue. In those with multiple sclerosis, greater effects of fatigue were seen.

Featured Neuroscience

·May 6, 2022·2 min read

Oligodendrocytes Arise in the Human Brain Earlier in Development

Researchers discovered oligodendrocytes, myelin-producing cells within the central nervous system, become established in the brain during early fetal development.

This shows a person's finger zapping a brain with electricity

Featured Neurology Neuroscience

·March 12, 2022·4 min read

Brain Cell Insight Could Lead to New Treatments for Neurological-Based Diseases

Study reports oligodendrocytes in the brain are distinct from oligodendrocytes in the central nervous system due to their metabolic processes. The findings may shed new light on neurological and autoimmune dysfunction in multiple sclerosis and other neurodegenerative disorders.

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myelin

Loosely Wrapped Myelin Marks Early Stages of Multiple Sclerosis, Even Before Inflammation

Intestinal Bacteria May Be an Important Piece in the Jigsaw Puzzle of Multiple Sclerosis

Myelin Determines Energy Metabolism in Inhibitory Brain Cells

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

New Drug a Hopeful Advance for Incurable Neurodegenerative Myelin Diseases

Alzheimer’s Risk Gene Undermines Insulation of Brain’s ‘Wiring’

New Method for Measuring Brain Activity Could Help Multiple Sclerosis Patients

Language Learning Difficulties in Children Linked to Brain Differences

Why Our Brain Wiring’s Insulation Matters

Signal Detection Theory May Be Useful for Characterizing Cognitive Fatigue in Multiple Sclerosis

Oligodendrocytes Arise in the Human Brain Earlier in Development

Brain Cell Insight Could Lead to New Treatments for Neurological-Based Diseases

Meditation Diminishes Bias Toward Negative Information

AI Can Predict Preterm Birth at 31 Weeks of Gestation

Middle Age Sexual Satisfaction: A Potential Early Sign of Cognitive Decline

Sleep Apnea’s Deep Impact on Gene Activity

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