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myelin

·November 28, 2023·6 min read

Redefining Myelin Damage

A new study explores the intricate relationship between myelin degeneration and neuron health. Contrary to the traditional view that demyelination primarily leads to axon degeneration, the study found that axons enwrapped in defective myelin are at a higher risk.

Featured Neuroscience

·September 23, 2023·7 min read

New Tools Illuminate Myelin Growth in Infants

Researchers are grappling with vast datasets to unravel brain mysteries. A team employed new software to analyze MRIs from 300 infants, revealing that myelin in white matter grows slower after birth.

Featured Genetics Neurology Neuroscience

·August 24, 2023·5 min read

Unlocking Myelin Regeneration

Researchers revealed a pivotal mechanism in myelin repair and regeneration, focusing on the Daam2 protein and CK2α kinase. Myelin, critical for efficient neurotransmission, when damaged leads to serious neurological diseases.

Featured Neurology Neuroscience

·June 17, 2023·3 min read

Pregnancy Hormone Estriol May Reverse Myelin Damage in Multiple Sclerosis

Treating a mouse model of multiple sclerosis (MS) with the pregnancy hormone estriol could reverse myelin breakdown in the brain's cortex, a primary area affected in MS. MS results in inflammation that damages the myelin coating around nerve fibers in the brain's cortex, leading to disability worsening.

Featured Neurology Neuroscience

·June 13, 2023·5 min read

Antihistamine Sparks Hope for Myelin Repair in Multiple Sclerosis

A new study paves the way for potential treatments for Multiple Sclerosis (MS) by identifying the OTC antihistamine, clemastine, as an effective drug for brain repair. Utilizing a newly-developed MRI scan technique, scientists were able to observe and measure the impact of clemastine on brain myelin levels.

Featured Neurology Neuroscience

·June 2, 2023·5 min read

Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

Age-related degeneration of myelin, the insulating layer around nerve cells in the brain, actively promotes disease-related changes in Alzheimer's. Researchers examined mouse models of Alzheimer's with myelin defects, finding that these defects accelerated the formation of amyloid plaques, a characteristic sign of Alzheimer's.

Featured Neurology Neuroscience

·May 25, 2023·6 min read

Loosely Wrapped Myelin Marks Early Stages of Multiple Sclerosis, Even Before Inflammation

Structural abnormalities in white matter, even before the onset of inflammation, may serve as a new therapeutic target for multiple sclerosis (MS). The study, focusing on 'normal-appearing white matter', identified early changes in myelin, an insulating substance around nerve fibers.

Featured Neurology Neuroscience

·January 5, 2023·5 min read

Intestinal Bacteria May Be an Important Piece in the Jigsaw Puzzle of Multiple Sclerosis

Study reveals differences in the composition and functionality of intestinal bacteria of multiple sclerosis patients depending on whether their illness is active or whether they are in treatment.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 20, 2022·4 min read

Myelin Determines Energy Metabolism in Inhibitory Brain Cells

In PV cells, axons with myelin contain more mitochondria. When myelin is decreased in PV cells, mitochondria also decrease. However, mitochondria increase when myelin is lost in excitatory cells.

Featured Neurology Neuroscience

·December 6, 2022·5 min read

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.

Featured Neuroscience

·December 2, 2022·3 min read

New Drug a Hopeful Advance for Incurable Neurodegenerative Myelin Diseases

Riluzole, an FDA-approved drug to treat ALS, can, in part, correct the molecular cause of some leukodystrophies.

This shows tissue samples from the study

Featured Genetics Neurology Neuroscience

·November 16, 2022·7 min read

Alzheimer’s Risk Gene Undermines Insulation of Brain’s ‘Wiring’

When people carry the Alzheimer's associated APOE4 gene, oligodendrocytes fail to transport fatty molecules to wrap neurons that make brain circuitry connections. This deficit of myelin may contribute to the pathology and symptoms of Alzheimer's disease.

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myelin

Redefining Myelin Damage

New Tools Illuminate Myelin Growth in Infants

Unlocking Myelin Regeneration

Pregnancy Hormone Estriol May Reverse Myelin Damage in Multiple Sclerosis

Antihistamine Sparks Hope for Myelin Repair in Multiple Sclerosis

Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

Loosely Wrapped Myelin Marks Early Stages of Multiple Sclerosis, Even Before Inflammation

Intestinal Bacteria May Be an Important Piece in the Jigsaw Puzzle of Multiple Sclerosis

Myelin Determines Energy Metabolism in Inhibitory Brain Cells

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

New Drug a Hopeful Advance for Incurable Neurodegenerative Myelin Diseases

Alzheimer’s Risk Gene Undermines Insulation of Brain’s ‘Wiring’

Heartbeat’s Influence on Brain Activity

Reshaping the OCD Brain: How Therapy Alters Neural Connectivity

Persistent Brain Repair Signals in Ex-NFL Players

Innovative Fiber to Tackle Alzheimer’s Developed

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