Researchers have identified high levels of three gut-produced toxic metabolites in plasma and cerebrospinal fluid samples of patients with multiple sclerosis.
A new review of almost 200 publications suggests the gut microbiota may play a critical role in modulating brain function, social behavior and other symptoms of autism.
Microglia, a key immune cell in the brain, appears to mediate the relationship between the gut microbiome and amyloid-beta deposits in male mouse models of Alzheimer's disease.
For people with arthritis, exercise reduces pain and lowers levels of inflammatory cytokines. Exercise also increases the production of natural endocannabinoids. Researchers found the way exercise promotes these changes was due to altered gut microbes.
A new study suggests the differences in the gut microbiome associated with autism may be a result of restricted dietary preferences, which are a common feature of ASD, rather than a cause of autism symptoms.
The vascular barrier in the choroid plexus locks down access to the brain in response to gut inflammation that causes IBD. The dysregulated activity of the gut-brain vascular axis appears to protect the brain from inflammation. However, the mechanism may increase the risk of both cognitive and mental health problems associated with IBD.
Study reveals a causal mechanism for pain reduction may be due to an antibiotic-induced shift in the gut's amino acid concentrations.
Fenchol, a natural compound found in basil and other plans, appears to have a neuroprotective effect against Alzheimer's disease. Fenchol reduces the formation of zombie neural cells and increases the degradation of non-functional amyloid beta, allowing for quicker clearance of the protein from the brain.
Children whose saliva produced high amounts of sulfur volatiles disliked raw Brassica vegetables the most. The levels of sulfur volatiles were similar in parents and children, suggesting a shared oral microbiome. However, the relationship between sulfur volatiles and the dislike of Brassica vegetables was not as high in adults, suggesting they may have learned to tolerate the taste of the vegetables over time.
An overgrowth in the gastrointestinal tract of the bacteria Klebsiella in preterm babies was associated with an increased presence of certain immune cells and the development of neurological damage. The findings suggest a link between microbiota and brain development.