Genetic mutations, which occur in both the brain and gut, could be a main cause of autism. Using mouse models of ASD, researchers discovered the neuroligin-3 R451C mutation affects neural communication in the brain and causes dysfunction in the gut. The findings strengthen the gut-brain hypothesis of autism.
A new mouse study reveals pups of mothers who faced prenatal stress and who were exposed, by birth, to maternal vaginal microbiota had decreased body weight and exhibited increased stress hormones as adults.
Researchers say that, despite taking a standardized diet consisting of a liquid meal replacement, gut bacteria change frequently and unpredictably.
Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.
Short-chain fatty acid supplementation improves stroke recovery in mouse models.
Researchers have successfully identified autism risk in young mice by examining their mother's microbiome during pregnancy. The study, which may offer the earliest detection of autism, could pave the way to developing preventative measures against forms of autism by altering the maternal diet and probiotic intake.
A new mouse study reveals common food additives, such as the dietary emulsifiers CMC and P80, may increase the risk of anxiety related disorders and adversely affect social behaviors.
A new study reports long term use of antibiotics in mice decreased levels of amyloid plaques and activated inflammatory microglial cells.
A new study reports gut bacteria drives the formation of cerebral cavernous malformations.