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IBD

·March 14, 2023·5 min read

Molecular Component of Caffeine May Play a Role in Gut Health

Xanthine, a purine metabolite found in caffeinated products such as coffee and tea, and in chocolate, appears to play a role in TH17 cell differentiation in the gut. The findings may lead to a better understanding of gut health and shed new light on the development of inflammatory disorders such as IBD.

Featured Neurology Neuroscience

·January 11, 2023·4 min read

An Education Doesn’t Just Make You Smarter, It Protects Your Gut

Better education has a strong genetic correlation and protective causal association against several disorders that affect the gut, a new study reports.

Featured Neuroscience Open Neuroscience Articles

·January 9, 2023·4 min read

Frequent Use of Antibiotics May Heighten Inflammatory Bowel Disease Risk in Adults Over 40

Adult exposure to antibiotics appears to be linked to an increased risk of developing an inflammatory bowel disorder, including Crohn's disease and ulcerative colitis. The risk appears to be cumulative, greatest around two years after use, and for antibiotics that target gut infections.

Featured Neuroscience

·October 14, 2022·4 min read

Pain-Sensing Gut Neurons Protect Against Inflammation

Pain-sensing neurons in the put secrete substance P, a molecule that protects against gut inflammation and tissue damage by boosting specific microbes in the gut. In people with inflammatory bowel disease, the pain-sensing neurons are diminished and there are significant disruptions in pain-signaling genes.

Featured Neuroscience Open Neuroscience Articles

·August 19, 2022·4 min read

How a Japanese Herbal Medicine Protects the Gut Against Inflammatory Bowel Disease

DKT, a Japanese herbal remedy containing ginger, pepper, ginseng, and maltose, reduced symptoms of colitis in mice, a new study reports.

Featured Neuroscience Psychology

·June 2, 2022·4 min read

A Bidirectional Link Between Inflammatory Bowel Disease and Depression

Patients diagnosed with inflammatory bowel disease are 9 times more likely to develop depression than those without IBD. Those with depression are twice as likely to develop inflammatory bowel disease, a new study reports.

Featured Neurology Neuroscience

·May 13, 2021·3 min read

Food Dyes May Cause Disease When the Immune System Is Dysregulated

Mice with cytokine IL-23 dysregulation who consumed foods containing the artificial colorants FD&C Red 40 and Yellow developed colitis, a new study reports.

Featured Genetics Neurology Neuroscience

·January 3, 2020·6 min read

Fat-dissolving bile acids may help regulate gut immunity and inflammation

Two studies reveal the role bile acids play in immunity and inflammation.

Featured Neurology Neuroscience Open Neuroscience Articles

·November 14, 2019·4 min read

Sugar binges increase risk of inflammatory bowel disease

Short term increases in sugar consumption raise the susceptibility to colitis and worsen symptoms of inflammatory bowel disease in mouse models.

Featured Neurology Neuroscience Open Neuroscience Articles

·November 14, 2019·5 min read

Inflammatory bowel disease appears to impact risk of Parkinson’s disease

Study provides new insights into how the immune system and inflammation play a role in the development and progression of Parkinson's disease.

Featured Neuroscience

·October 24, 2019·5 min read

Gut instincts: Researchers discover first clues on how gut health influences brain health

Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems.

This shows the outline of two children's heads

Featured Neuroscience Psychology

·August 19, 2019·6 min read

Increased risk of psychiatric disorders in children with inflammatory bowel disease

Children with inflammatory bowel disease (IBD) are at increased risk of being diagnosed with a mental health problem. The risk of being diagnosed with a psychiatric condition is 1.6 times higher for those with IBD than the general population. IBD is associated with an increased risk of eating disorders, anxiety, depression, personality disorders, and ASD diagnosis. Researchers report there is also an increased risk of suicidal thoughts when the child reaches adulthood. The risk of being diagnosed with a psychiatric disorder was highest during the first year of IBD diagnosis, especially in children diagnosed with the condition before the age of 6.

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IBD