Study reveals a motif on the 93-series compound fits into a tiny pocket within the NMDA receptor. The findings could lead to new treatment options for stroke and seizures, researchers report.
Researchers have identified some of the key neurobiological mechanisms that help keep aggression under control. The findings could help develop targeted treatments to help those with aggressive problems associated with psychological disorders.
A new study reports increased levels of STEP in the hippocampus is linked to mild cognitive impairment.
Using CRISPR gene editing technology, researchers target the Shank3 gene in monkey embryos. Research backs previous findings of the importance of the Shank3 gene for brain development and its role in autism.
A new study could guide anticonvulsant treatment for some people with genetic epilepsy with repurposed Alzheimer's medications.
Researchers have discovered a previously unknown mechanism that allows neural networks to protect against the spread of secondary brain damage as seen in TBI and ischemic stroke.
Researchers discover the xanthohumol, a flavinoid found in hops, can improve cognitive function in young mice but not in older animals.
Researchers discover a gene already associated with longevity also improves memory and learning. The findings could help develop new treatments for cognitive decline.
A new study has identified neural circuits in mice which are involved in the learning and altering of behaviors. The findings could have implications for alcoholism and other addictive behaviors.
A new study provides clues into how the function of the most common NMDA receptor subtypes may be manipulated for clinical benefit. NMDA receptors have been implicated in a number of neurological and psychological disease, from Alzheimer's to schizophrenia.