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anesthesia

·January 12, 2023·3 min read

Predisposition to Accidental Awareness Under Anesthesia Identified

As many as one in four patients who receive anesthesia may suffer accidental awareness during their procedure. Researchers have identified specific brain structures that may predict whether a person will experience accidental awareness under anesthesia. The findings will help identify patients who require higher than average doses of anesthesia.

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·October 11, 2022·5 min read

Why Are Sounds Not Perceived Under Anesthesia?

Under anesthesia, neuron assemblies that respond to sound become indistinguishable from spontaneously active neurons. Findings suggest the state of unconsciousness produced by anesthesia forces the cerebral cortex to mask sensory input with spontaneous neural activity.

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·May 24, 2022·4 min read

Rhythmical Deep Sleep

Researchers investigate the influence anesthesia has on brain functions.

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Featured Neuroscience

·May 22, 2022·2 min read

Cannabis Users Require More Sedation for Endoscopy

Cannabis users undergoing gastric endoscopy procedures generally require more sedation than non-cannabis users, researchers report.

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·May 12, 2022·5 min read

When Unconscious, the Brain Is Anything but ‘Silent’

Some neurons in the cerebral cortex show higher spontaneous activity during general anesthesia than when awake, and this activity is synchronized across the cortical cells.

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·September 13, 2021·3 min read

Mimicking Nature to Provide Long-Lasting Local Anesthesia

A new bio-inspired slow-release system for site 1 sodium channel blockers helps release anesthesia, providing prolonged nerve blocking with minimal toxicity.

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·September 3, 2021·6 min read

Statistical Model Defines Ketamine Anesthesia’s Effects on the Brain

A new statistical model lays groundwork for understanding how ketamine induces an anesthetic response, steps to monitor unconscious patients, and provides new information about brain activity while unconscious.

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·May 29, 2021·4 min read

Escape From Oblivion: How the Brain Reboots After Deep Anesthesia

Following deep anesthesia, consciousness and cognitive processes unfold over time. The prefrontal cortex is the first brain area to recover, with areas associated with reaction time and attention taking longer to return to pre-anesthesia states.

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·May 7, 2021·7 min read

Algorithms Show Accuracy in Gauging Unconsciousness Under General Anesthesia

A newly developed artificial intelligence algorithm can accurately and reliably assess unconsciousness in patients under anesthesia based on brain activity.

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·April 27, 2021·5 min read

Anesthesia Doesn’t Simply Turn Off the Brain, It Changes Its Rhythms

Propofol, the commonly used anesthetic, alters and controls the dynamics of the brain's rhythms. The findings can help doctors better monitor patients under anesthesia with the aid of EEG.

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·March 16, 2021·5 min read

A Better Way to Measure Consciousness

Researchers recorded the electrical activity in over 1000 neurons around 100 sites of the brain during different states of consciousness in monkeys. The results were analyzed by machine learning. Results pointed away from the prefrontal cortex, an area monitored to safely maintain general anesthesia, and toward areas at the back of the brain. The study reveals deep brain and areas toward the back of the brain are more predictive of states of consciousness.