New Drug Enhances Radiation Treatment for Brain Cancer in Preclinical Studies
A new drug could help increase the effectiveness of radiation therapy for patients with glioblastoma multiforme, the most deadly form of brain cancer. The ATM kinase inhibitor, in combination with radiation therapy, helped significantly extend survival rates in mouse models of GBM.
Scientists Find Potential Therapeutic Target for Cushing’s Disease
Researchers have identified that the TR4 protein, which regulates a gene that produces ACTH, drives the formation of pituitary tumors in Cushing’s disease.
Using Fat to Fight Brain Cancer
Researchers discover stem cells from a patient’s own fat could potentially deliver new treatments directly to the brain after the removal of a glioblastoma, the most common form of brain cancer.
New Chemical Probe Provides Tool to Investigate Role of Malignant Brain Tumor Domains
Researchers announce the discovery of a chemical probe, UNC1215, which could be used to investigate the function of malignant brain tumor domain proteins.
Novel Combination Therapy Shuts Down Escape Route, Killing Glioblastoma Tumor Cells
A new study discovers molecular pathways that could lead to new targeted therapies which may potentially treat Glioblastoma, the most common and lethal form of brain cancer in adults.
Neuroscientist Sheds Light on Cause for ‘Chemo Brain’
A new study argues that prolonged chemotherapy decreases the development of new brain cells, and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories.
Caught in the Act: Researchers Capture Key Moments in Cell Death
Researchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.
Dendritic Cell Vaccine for Relapsed Neuroblastoma Patient Induces Complete Remission
Cancer treatment vaccine research leads to remission in a child with a relapsed neuroblastoma.
Genetic Landscape of Common Brain Tumors Holds Key to Personalized Treatment
Researchers discover the genetic landscape of the most common form of brain tumor can be explained by abnormalities in five genes. The finding could help to develop personalized medical therapies and treatment options.
Researchers Identify Enzyme Involved in Deadly Brain Tumors
In a study published in Neuro-Oncology, researchers at Mayo Clinic identify an important association between the naturally occurring enzyme Kallikrein 6, also known as KLK6, and glioblastoma multiforme tumors.
