Nanotechnology treatment reverses multiple sclerosis in mice
Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.... Read More...
stem cells
Intranasal stem cell therapy restores smell in mice
The sense of smell has been restored to mice suffering olfactory problems with the aid of stem cell therapies. The findings provide the basis for transitional research to see whether intranasal stem cell treatments can be beneficial for those who have lost their sense of smell.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
Targeting key gene could help lead to down syndrome treatment
Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development. ... Read More...
Pigment-producing stem cells can regenerate myelin sheath: Mouse study
Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.... Read More...
Restoring brain function in mice with symptoms of Alzheimer’s disease
Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.... Read More...
Proteins stand up to nerve cell regression
Study reveals the critical and novel roles Integrator complex proteins play in promoting healthy brain development in flies. ... Read More...
Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment
Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.... Read More...
Researchers discover crucial link between brain and gut stem cells
The insulin-like growth factor II gene plays a critical role in adult stem cell maintenance of both the intestine and the brain. Findings suggest IGF-2 is essential for multiple stem cell types, including those implicated in cognitive function and renewing the lining of the small intestine.... Read More...
Parkinson’s clues seen in tiny fish could aid quest for treatments
Zebrafish study reveals how key dopaminergic neurons, which are damaged as a result of Parkinson's disease, can be regenerated. Researchers report the immune system plays a critical role in the process.... Read More...
Single Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse Study
The findings support a continuous model of neurogenesis throughout development and adulthood.... Read More...
Discovery of the Genetics Conductor of Brain Stem Cells
Researchers describe their findings about how the Foxg1 gene is involved in the development and differentiation of neurons and glial cells from stem cells.... Read More...