Scientists reverse aging process in rat brain stem cells
Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.... Read More...
stem cells
Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.... Read More...
To become, or not to become… a neuron
Bcl6 acts as a driver of neurogenic transition by directly silencing a selection of genes that belong to multiple extrinsic pathways promoting self-renewal. Bcl6 is only expressed in specific subsets of neurons and progenitor cells during brain development.... Read More...
Study looks at stem cells for answers to how a type of autism develops
Stem cell study reveals a genetic defect associated with fragile X syndrome delays the production of neurons during a critical stage of embryonic development. ... Read More...
Discovery of the cell fate switch from neurons to astrocytes in the developing brain
The FGF signaling pathway is an important extracellular regulator in the fate of neural stem cells switching from neurons to astrocytes in the cerebral cortex. ... Read More...
Dormant neural stem cells in fruit flies activate to generate new brain cells
Awakening dormant stem cells could stimulate the growth of new neurons. The findings could have significant implications for the treatment of neurodegenerative diseases.... Read More...
Stem cells reprogrammed into neurons could reveal drugs harmful to pregnancy
A new experimental system which uses embryonic stem cells reprogrammed into neurons has the potential to assess the pathogenic effects of a drug on brain development.... Read More...
Nanotechnology treatment reverses multiple sclerosis in mice
Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.... Read More...
Intranasal stem cell therapy restores smell in mice
The sense of smell has been restored to mice suffering olfactory problems with the aid of stem cell therapies. The findings provide the basis for transitional research to see whether intranasal stem cell treatments can be beneficial for those who have lost their sense of smell.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
Targeting key gene could help lead to down syndrome treatment
Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development. ... Read More...
Pigment-producing stem cells can regenerate myelin sheath: Mouse study
Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.... Read More...