In Parkinson's disease, alpha synuclein clumps move to and damage mitochondrial proteins, making them less efficient and causing the mitochondrial to burst, leaking out chemicals that tell the cells to die, researchers say.
Researchers report altering synaptic plasticity leads to a computational switch in a hippocampal synapse which turns the presynaptic neuron turns into “detonator” mode, causing it to fire more readily.
Researchers have identified a protein embedded in the surface of mitochondria that opens the door to cell death.
