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Brain changes linked with Alzheimer’s up to 30 years before symptoms appear

Neuroscience News
Researchers have identified average levels of biological and anatomical brain changes associated with Alzheimer's disease over thirty years before symptoms appear. In those with genetic risk factors for Alzheimer's, researchers found changes in cognitive performance up to 15 years before becoming symptomatic. Changes in Tau levels in the cerebral spinal fluid appeared up to 34 years before dementia symptoms occurred, and physical changes to the medial temporal lobe were apparent up to 9 years before cognitive impairment was apparent.... Read More...
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles5 min read
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When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

Neuroscience News
LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.... Read More...
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles6 min read