Researchers propose a novel computational framework that uses artificial intelligence technology to disentangle the relationship between perception and memory in the human brain.
Frequent caffeine consumption reduces gray matter volume in areas of the right medial temporal lobe, including the hippocampus. Ten days of "caffeine abstinence" helps regenerate gray matter.
Neurons in the medial prefrontal cortex respond more to loss than to gain. Avoidance of risk-taking is affected by an area of the hippocampus that is associated with memory and anxiety. The findings suggest a close relationship between memory processing and decision making when risk is present, especially in stressful situations. The fresh insights might help guide new psychiatric therapies for disorders marked by excessive avoidance, such as anxiety, and depression, and also mania and addiction, where excessive risk-taking is a common feature.
Researchers have uncovered the neural mechanism underlying rumination. The study reports when rumination occurs, coupling between the core and medial temporal lobe subsystems of the default mode network becomes elevated, while coupling between the core and dorsomedial prefrontal cortex decreases.
Some words are far more memorable than others. Researchers discovered our memories are wired into neural networks that allow the brain to search for these memories, much like the way search engines track down relevant information.
The medial temporal lobe and medial parietal cortex work in tandem to assist in the recognition of faces and places.
APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.
Hangxiety, the feeling of waking up with anxiety the morning after heavy drinking, is a common symptom associated with a hangover. Researchers explain how a heavy night's drinking alters neurochemistry, leaving some of us prone to waking with anxiety.
Neural activity in the entorhinal cortex is correlated with place-based memories. The findings shed new light on how the brain processes spatial memory.
Imagination helps us act altruistically, a new study reports. When we see others in trouble, we imagine how we can help before acting. Researchers implicate the medial temporal lobe subsystem in guiding our prosocial behaviors.