medial temporal lobe

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medial temporal lobe

Featured Neuroscience Open Neuroscience Articles

·September 1, 2020·4 min read

Study Sheds Light on Brain Mechanism Activated by Uncertainty

Neurons in the medial prefrontal cortex respond more to loss than to gain. Avoidance of risk-taking is affected by an area of the hippocampus that is associated with memory and anxiety. The findings suggest a close relationship between memory processing and decision making when risk is present, especially in stressful situations. The fresh insights might help guide new psychiatric therapies for disorders marked by excessive avoidance, such as anxiety, and depression, and also mania and addiction, where excessive risk-taking is a common feature. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·August 29, 2020·3 min read

Researchers Uncover Network Mechanism Underlying Rumination

Researchers have uncovered the neural mechanism underlying rumination. The study reports when rumination occurs, coupling between the core and medial temporal lobe subsystems of the default mode network becomes elevated, while coupling between the core and dorsomedial prefrontal cortex decreases. Read More

Featured Neuroscience

·July 2, 2020·9 min read

Why Some Words May Be More Memorable than Others

Some words are far more memorable than others. Researchers discovered our memories are wired into neural networks that allow the brain to search for these memories, much like the way search engines track down relevant information. Read More

Featured Neuroscience Open Neuroscience Articles

·June 4, 2020·4 min read

New study reveals areas of brain where recognition and identification occur

The medial temporal lobe and medial parietal cortex work in tandem to assist in the recognition of faces and places. Read More

Featured Genetics Neurology Neuroscience

·April 29, 2020·4 min read

APOE4 triggers early breakdowns in the blood-brain barrier

APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's. Read More

Featured Neuroscience Psychology

·January 1, 2020·3 min read

New Year’s anxiety hangover? Here’s what’s happening in your brain

Hangxiety, the feeling of waking up with anxiety the morning after heavy drinking, is a common symptom associated with a hangover. Researchers explain how a heavy night's drinking alters neurochemistry, leaving some of us prone to waking with anxiety. Read More

Featured Neuroscience Neuroscience Videos

·November 12, 2019·5 min read

Specific neurons that map memories now identified in the human brain

Neural activity in the entorhinal cortex is correlated with place-based memories. The findings shed new light on how the brain processes spatial memory. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·July 12, 2019·5 min read

The brain’s pathways to imagination may hold the key to altruistic behavior

Imagination helps us act altruistically, a new study reports. When we see others in trouble, we imagine how we can help before acting. Researchers implicate the medial temporal lobe subsystem in guiding our prosocial behaviors. Read More

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Featured Neurology Neuroscience Open Neuroscience Articles

·May 14, 2019·4 min read

Brain changes linked with Alzheimer’s up to 30 years before symptoms appear

Researchers have identified average levels of biological and anatomical brain changes associated with Alzheimer's disease over thirty years before symptoms appear. In those with genetic risk factors for Alzheimer's, researchers found changes in cognitive performance up to 15 years before becoming symptomatic. Changes in Tau levels in the cerebral spinal fluid appeared up to 34 years before dementia symptoms occurred, and physical changes to the medial temporal lobe were apparent up to 9 years before cognitive impairment was apparent. Read More

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Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·5 min read

When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone. Read More