Women who breastfeed have a reduced risk of developing diabetes, a new study reports. In mouse models, lactation improved glucose tolerance and increased beta-cell mass three weeks post-delivery. Prolactin produced as a result of lactation induced serotonin production of beta cells. Findings suggest serotonin mediates the long-term beneficial effects of lactation of female metabolic health by increasing beta-cell proliferation and reducing oxidative stress in beta-cells.
During lactation, the cell voltage of TIDA neurons in the hypothalamus oscillates more frequently, increasing firing. The change is reversible and returns to normal once the mother stops lactating.
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Ranibizumab and aflibercept, two drugs used to treat retinal diseases, are excreted in the breast milk of nursing mothers who take the medications. The drugs contain an agent called anti-vascular endothelial growth factor (anti-VEGF), which blocks the development of a protein which stimulates the development of blood vessels. The protein, VEGF, is present in breast milk and plays a role in the development of the digestive system in infants.
Researchers report binge drinking during pregnancy and lactation may result in an increased risk of mood problems and alcohol abuse in offspring as they reach adolescence.
BPS affects a neuroanatomy and maternal behavior in pregnant and lactating mice, including an association with an increased risk of infanticide.