Parkinson's patients have reduced acylated-ghrelin to unacylated-ghrelin ratios in their blood. Lower levels of unacylated-ghrelin have been associated with a reduced ability to generate new neurons and memory impairments. Read More
The hunger hormone ghrelin doesn't just influence where and when animals eat, it also appears to have an impact on memory. Disrupting signaling of ghrelin to the vagus nerve caused rats to forget they had just eaten, even though the animals remembered they had just had access to food. Findings suggest disrupted ghrelin signaling could negatively impact episodic memory. Read More
The risk of developing PTSD was eight times higher in teens who experienced traumatic events and had elevated acyl-ghrelin levels than trauma-exposed teens with lower levels of the hormone. Read More
A study that used postmortem brain tissue samples from Alzheimer's patients and mouse models found the hunger hormone ghrelin is linked to cognitive impairments and memory loss associated with the disease. Read More
Utilizing mealtime strategies, such as intermittent fasting or early eating, can help improve fat burning and reduce appetite. Those who practice early eating restricted feeding strategies had lower levels of ghrelin and improved fat burning. Read More
Researchers have identified neurons in the guts of C. elegans that detect when bacteria are ingested and release a neurotransmitter that signals the brain to halt locomotion. Read More
Researchers discover activity in brain regions involved in reward response from dopamine was higher in subjects injected with the hormone ghrelin, but only when responding to images associated with food smells. The study reports ghrelin controls the extent to which the brain associates reward with food odors. Read More
Researchers debate the roles of the gut and brain hormones play in regulating appetite and metabolism. Read More
Researchers have identified a signaling pathway that appears to be responsible for hunger. Targeting the pathway, researchers say, could be key to finding new treatments to curb obesity. Read More
A new neuroimaging study found those who achieved greater success at losing weight showed increased activation in regions of the lateral prefrontal cortex, an area of the brain associated with self control. Read More
According to researchers, neurons generated from super obese people are more likely to dysregulate hormones related to hunger and feeding behaviors. Read More
NPGL, a newly discovered molecule, increases appetite during periods of fasting and decreases it when we gorge, researchers report. Read More
