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estrogen

·July 6, 2026·9 min read

Early Pregnancy Hormones Predict IQ

A new study proves that maternal estrogen levels at 6–8 weeks of pregnancy directly predict a newborn's head circumference, with a stronger effect in boys. The findings support the "estrogenized ape hypothesis," suggesting that human brain expansion is evolutionarily linked to prenatal estrogenization, carrying an evolutionary trade-off of reduced male health and fertility.

Featured Neuroscience

·June 23, 2026·12 min read

Lifetime Estrogen Exposure Shields Women from Brain Atrophy

A new study demonstrates that lifetime estrogen accumulation, from early-life birth control, late menopause, or hormone therapy, protects brain health in older women, resulting in larger memory center volumes and thicker cortices.

Featured Neuroscience

·June 9, 2026·8 min read

Mapping the Brain’s Resting Grid Through Menopause

A new study confirms that the menopausal transition represents a critical neurological phase.

Brain Cancer Featured Neuroscience

·June 8, 2026·6 min read

Disrupting Cancer Drug’s Cognitive Decline Loop

A new study demonstrates that the estrogen prodrug DHED protects memory and sleep without risking cancer recurrence.

Featured Neurology Neuroscience

·May 26, 2026·11 min read

Estrogen Loss May Drive Female Alzheimer’s

Post-menopausal estrogen loss triggers an environmental collapse in the "extracellular matrix" (ECM), the long-overlooked molecular scaffold that fills 20% of the brain's volume and regulates cellular communication within the hippocampus.

Featured Genetics Neuroscience

·May 10, 2026·5 min read

Progesterone Exposure Linked to Gene Alterations in Male Brains

A new study in sheep models shows that male fetuses exposed to high levels of progesterone experience an accumulation of the SRD5A1 gene in the frontal cortex. These findings emphasize the importance of understanding how prenatal hormone exposure shapes neural pathways and predisposes offspring to various health outcomes later in life.

This shows the outline of two women's heads and a brain.

Featured Neurology Neuroscience

·April 20, 2026·8 min read

Multiple Pregnancies May Shield the Female Brain From Stroke

A new study reveals that women with three or more live births have a reduced risk of stroke and covert vascular brain damage.

Featured Neuroscience Psychology

·April 12, 2026·11 min read

Estrogen Levels at the Moment of Trauma Predict PTSD

High estrogen levels at the moment of trauma increase the brain's "plasticity," making it more vulnerable to PTSD. This biological state helps explain why women face higher PTSD risks.

This shows the outline of a woman's head.

Autism Featured Neuroscience

·April 9, 2026·8 min read

Why Autism Is Less Frequent in Women

Researchers discovered that the MDGA1 gene mutation causes autism primarily in males, while females are protected by estrogen. The study suggests bazedoxifene, an FDA-approved drug, could be a new treatment for ASD.

Featured Neuroscience

·November 12, 2025·5 min read

Estrogen Shapes Dopamine Reward Learning

A new study shows that estrogen naturally modulates dopamine signaling in the brain, altering how female rats learn reward cues across the reproductive cycle. When estrogen levels were high, dopamine responses in the reward center intensified, improving learning.

Featured Neurology Neuroscience

·October 14, 2025·6 min read

Pregnancy Hormones Show Promise in Treating Progressive MS

Researchers have identified two forms of estrogen, estradiol and estriol, that may reduce inflammation and protect nerve fibers in progressive multiple sclerosis (MS). Using a virus model of the disease, the study found that both hormones lowered spinal cord inflammation, while estradiol significantly preserved the myelin sheath that protects nerve cells.

Featured Neuroscience

·April 14, 2025·4 min read

How Lactating Brains Rewire Metabolism for Milk Production

Lactation triggers significant metabolic changes in mothers, driven by shifting hormone levels and brain activity. Researchers have now uncovered how increased prolactin and reduced estrogen suppress specific neurons in the hypothalamus to boost appetite and conserve fat, meeting the energy demands of nursing.

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estrogen

Early Pregnancy Hormones Predict IQ

Lifetime Estrogen Exposure Shields Women from Brain Atrophy

Mapping the Brain’s Resting Grid Through Menopause

Disrupting Cancer Drug’s Cognitive Decline Loop

Estrogen Loss May Drive Female Alzheimer’s

Progesterone Exposure Linked to Gene Alterations in Male Brains

Multiple Pregnancies May Shield the Female Brain From Stroke

Estrogen Levels at the Moment of Trauma Predict PTSD

Why Autism Is Less Frequent in Women

Estrogen Shapes Dopamine Reward Learning

Pregnancy Hormones Show Promise in Treating Progressive MS

How Lactating Brains Rewire Metabolism for Milk Production

Mediterranean Diet Boosts Psychological Well-Being Over Age 50

Exoskeleton Reads Faint Muscle Signals to Overcome Hand Paralysis

Invisible Tire Dust Hijacks Alzheimer’s Predictor Genes

Multilingualism Subtracts Up to 13 Years from Brain Age

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