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DGIST

·September 8, 2025·4 min read

Wireless Implant Delivers Drugs Deep in Brain

Researchers have developed a wireless, implantable neural interface that can deliver drugs directly to deep brain regions with precision. The device uses a soft, flexible micro-pump and channel design to ensure controlled, backflow-free infusion without external equipment.

Autism Featured Genetics Neuroscience

·May 20, 2025·5 min read

Newly Found Brain Switch Regulates Synapses, Offers Clues to Autism

A research team has uncovered a molecular "switch" that precisely regulates NMDA receptors, key players in brain communication, by blocking excitatory synapse overactivity. The proteins MDGA2 and EphB2 were found to compete for receptor activation, with MDGA2 acting as a natural inhibitor.

This shows the outline of a person and neurons.

Autism Featured Neuroscience Psychology

·May 19, 2025·4 min read

Inflammation Triggers Repetitive Behaviors in ASD and OCD

New research reveals that chronic brain inflammation can directly lead to repetitive behaviors, often seen in conditions like autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD). In mice with a mutated NLRP3 gene, inflammation activated microglia to release IL-1β, overstimulating NMDA glutamate receptors responsible for excitatory brain signals.

Featured Neuroscience Psychology

·December 6, 2024·4 min read

Astrocytes Hold the Key to Stress Response Regulation

Astrocytes, previously known for supporting nerve cells, have been identified as key regulators of stress responses in the lateral septum of the brain. Researchers demonstrated that astrocytes release adenosine to suppress nearby nerve activity when exposed to stress-inducing stimuli. This groundbreaking finding reveals that astrocytes interact dynamically with neurons to influence fear, anxiety, and social behaviors, varying based on the stress type and brain region.

Featured Neuroscience

·August 2, 2024·4 min read

Study Reveals Dopamine’s Limited Role in Rapid Neural Activity

A recent study has found that dopamine signals have a minimal impact on rapid neural activity in the striatum, challenging existing theories about dopamine's role in brain signaling. Using advanced optical neural chip technology, researchers observed that dopamine signals within normal physiological ranges do not significantly affect neural processing.

Autism Featured Neuroscience

·September 20, 2023·5 min read

Genetics, Drug Reactions, and Environmental Factors Linked to Autism Development

A collaborative research effort delved deeper into the environmental factors impacting autism spectrum disorder (ASD) onset. Utilizing a mouse model treated with valproate, researchers observed an increase in the expression of the Rnf146 gene, a known ASD influencer, in the mouse's prefrontal lobe.

Autism Featured Genetics Neuroscience

·December 14, 2022·3 min read

Found ‘Clue’ That Can Fundamentally Treat Autism Spectrum Disorder

A newly discovered cell-specific molecular network associated with ASD could lay the groundwork for finding an effective treatment for those with autism.

Featured Genetics Neurology Open Neuroscience Articles

·September 15, 2021·3 min read

Stem Cells Model Genetic Risk for Developing Alzheimer’s Disease

Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.

Featured Neuroscience Psychology

·August 13, 2021·4 min read

How a Specific Synapse Type Regulates Anxiety-Like Behavior

Study identifies the role a specific protein plays in regulating the development of inhibitory synapses in the hippocampus in the context of anxiety-related behaviors.

Featured Neurology Neuroscience

·February 25, 2021·2 min read

How Amyloid Beta Contributes to Loss of Smell in Alzheimer’s Disease

Regions of the olfactory system in mice with higher amyloid beta expression exhibited lower activation of olfactory sensory neurons and decreased odor detection.

Featured Neurology Open Neuroscience Articles

·August 11, 2020·3 min read

Right Under Your Nose: A More Convenient Way to Diagnose Alzheimer’s

Analyzing nasal discharge could be a new tool in diagnosing and monitoring the progression of Alzheimer's disease. Researchers found certain Alzheimer's related proteins can be detected in nasal discharge.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·August 9, 2019·3 min read

How chronic stress causes brain damage

Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.

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