The side effects of treating neurological disorders with antisense oligonucleotides (ASOs) are caused by calcium imbalances in the brain. Such side effects can be improved by the use of calcium-balance modulators.
Neural networks play a key role in regulating circadian rhythms through the mediation of cAMP. The findings may help with developing new strategies to manage circadian rhythm problems such as sleep disorders.
Pulsed electronically generated electromagnetic fields (EMFs) used for wireless communications produce electric and magnetic forces that act in the body's cells by activating voltage-gated calcium channels (VGCCs). VGCC activation induces changes that increase intracellular calcium levels. Researchers link EMF exposure to changes that lead to excessive intracellular calcium. This could have implications for the development of Alzheimer's disease.
Astrocytes can alter neurons to drive behaviors associated with ADHD. Researchers believe astrocytes may be used to develop targeted treatments for behavioral deficits associated with a range of mental illnesses.