Ambroxol, a common medicine used to treat respiratory illnesses shows promise as a treatment to slow the progression of Parkinson's disease. Researchers report ambroxol increases the level of GCase, a protein that allows cells to remove waste proteins including alpha synuclein.
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The shape of a specific set of proteins differs in the spinal fluid of patients with Parkinson's disease compared to those without the neurodegenerative disease.
People who lost weight soon after being diagnosed with Parkinson's disease had a more rapid decline in thinking skills compared to those who maintained their normal weight. Those who gained weight had a slower decline in cognitive skills.
Researchers discovered personal odors can alter in people with Parkinson's disease. Based on this, they identified specific markers for Parkinson's in sebum, an oily substance secreted from the skin. They developed a new, non-invasive swab test that can identify Parkinson's with 95% accuracy.
Researchers successfully turned skin cells from Parkinson's patients into dopaminergic neurons by introducing a combination of neural-inducing genes into the skin cells.
A newly developed artificial intelligence model can detect Parkinson's disease by reading a person's breathing patterns. The algorithm can also discern the severity of Parkinson's disease and track progression over time.
Adding to previous research on the gut-brain axis link to Parkinson's disease, researchers discovered the gut microbiome is involved with multiple pathways in the pathogenesis of Parkinson's.
Water plays a key role in how proteins associated with Parkinson's disease fold, clump or misfold.
Post-mortem analysis of the brains of those with Parkinson's disease revealed more than 200 genes with different epigenetic markers compared to healthy brains, but the affected genes were almost entirely different between women and men.
A new in-home device that monitors movement and gait speed can evaluate Parkinson's disease severity, progression, and a patient's response to medication.
Irisin, a hormone secreted into the blood during high endurance and aerobic exercise, reduces levels of alpha-synuclein and restores movement in mouse models of Parkinson's disease.
Cellular changes associated with Parkinson's disease could be revealed with the use of quantitative MRI which allows for a deeper examination of microstructures within the striatum.