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Pain

Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·February 2, 2023·7 min read

Antidepressants Use for Chronic Pain on the Rise, but Are They Effective?

SNRI antidepressants appear to be effective in the treatment of a range of pain conditions including neuropathic pain, fibromyalgia, and postoperative pain. Tricyclic antidepressants may not be effective in the treatment of pain.

Featured Neuroscience Pain Psychology

·November 13, 2024·4 min read

Are Emotional Sounds Universal Across Languages?

A new study examined vocal expressions of emotion across 131 languages, exploring similarities in emotional interjections and comparing them to non-linguistic sounds like cries and laughter. The research aimed to understand whether shared vocal patterns exist globally and if these patterns relate to our evolutionary roots in vocal communication. The team found that vocal expressions of pain, like "Ouch!", showed consistent vowel forms across languages, while disgust and joy did not.

Featured Neurology Neuroscience Pain

·July 7, 2023·5 min read

Arthritis-Related Joint Pain Varies Dramatically Across U.S. States

A new study highlights substantial state-by-state differences in arthritis-related joint pain across the US, from a low of 6.9% in Minnesota to a high of 23.1% in West Virginia. States in the South, the lower Mississippi Valley, and southern Appalachia show a particularly high prevalence of joint pain.

Autism Featured Neurology Pain

·December 1, 2016·5 min read

Autism Linked Protein Crucial For Feeling Pain

TRPV1 and SHANK3 could play a role in pain insensitivity in people with autism, a new study reports.

Featured Neurology Open Neuroscience Articles Pain

·November 30, 2017·5 min read

Behavior Not Indicative of Pain in Stressed Babies

A new study reveals newborns who are stressed by their environment have a greater neural pain response following a routine skin lance than babies who are not stressed. However, the neural response is not matched by their physical reaction to pain.

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·May 11, 2022·4 min read

Blocking Inflammation May Lead To Chronic Pain

Anti-inflammatories may relieve pain in the short term, but blocking inflammation can lead to longer-term chronic pain, a new study reports.

Featured Neurology Neuroscience Pain

·March 13, 2019·5 min read

Blunting pain’s emotional component

Blocking the release of dynorphin, researchers restore motivation in animals experiencing pain. The findings may help in the development of new, less addictive, pain medications.

Featured Neurology Neuroscience Pain

·May 22, 2023·6 min read

Brain Activity Reveals Chronic Pain Signatures

Researchers successfully recorded data directly from the brains of individuals suffering from chronic pain caused by stroke or amputation. This milestone, accomplished using machine learning tools, identified specific brain regions and biomarkers associated with chronic pain. The findings mark a significant stride towards devising novel methods for monitoring and treating chronic pain.

Featured Neurology Neuroscience Pain

·April 2, 2026·9 min read

Brain Circuit That “Invents” Chronic Pain Identified

Neuroscientists have identified a dedicated brain circuit responsible for chronic pain. By silencing this loop, researchers were able to end pain hypersensitivity in mice without affecting their ability to feel necessary, acute pain.

Featured Neuroscience Pain Psychology

·October 18, 2021·5 min read

Brain Circuitry Identified That May Be Responsible for Negative Emotional Aspects of Pain

A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.

Featured Neuroscience Open Neuroscience Articles Pain Psychology

·June 13, 2022·4 min read

Brain Differences in Pain Modulation in People With Self-Injury Behavior

On average, women who self-harm have a higher tolerance to pain than those who do not self-injure. Brain scans revealed greater connectivity between brain areas involved in pain perception and pain modulation in those who self-harm.

This shows a brain and neurons representing pain.

Featured Neurology Neuroscience Pain

·March 5, 2025·4 min read

Brain Distinguishes Pain and Itch Using Separate Neural Circuits

A new study reveals that pain and itch are processed by distinct neural circuits in the anterior cingulate cortex (ACC). Researchers identified two types of neurons—one responding to both stimuli and another selectively activated by either pain or itch.

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Pain

Antidepressants Use for Chronic Pain on the Rise, but Are They Effective?

Are Emotional Sounds Universal Across Languages?

Arthritis-Related Joint Pain Varies Dramatically Across U.S. States

Autism Linked Protein Crucial For Feeling Pain

Behavior Not Indicative of Pain in Stressed Babies

Blocking Inflammation May Lead To Chronic Pain

Blunting pain’s emotional component

Brain Activity Reveals Chronic Pain Signatures

Brain Circuit That “Invents” Chronic Pain Identified

Brain Circuitry Identified That May Be Responsible for Negative Emotional Aspects of Pain

Brain Differences in Pain Modulation in People With Self-Injury Behavior

Brain Distinguishes Pain and Itch Using Separate Neural Circuits

How Severe Illness During Pregnancy Alters Fetal Brain Development

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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