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Pain

Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

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·November 3, 2016·4 min read

Tuning the Brain to Alleviate Pain

According to researchers, both visual and auditory stimulation can significantly induce pain intensity.

Featured Neurology Pain

·September 14, 2020·4 min read

Turmeric Supplement More Effective Than Placebo for Osteoarthritis Knee Pain

An extract of turmeric is more effective than a placebo at reducing pain in those with knee osteoarthritis. Following 12 weeks of exposure to the extract, people reported less pain than those taking a placebo.

Featured Neurology Neuroscience Pain

·April 16, 2023·5 min read

Turning Down the Volume of Pain: How to Retrain Your Brain When You Get Sensitized

For those with chronic pain, it may be possible to retrain your brain to help manage or reduce your symptoms when you become over-sensitized to other treatment methods.

This shows a person holding their back in pain

Featured Neuroscience Open Neuroscience Articles Pain

·November 12, 2022·3 min read

Two Fifths of People Have Chronic Pain by Their 40s, With Consequences for Later Life

People who experience chronic pain during middle age report poorer mental and overall health problems later in life.

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·May 17, 2025·4 min read

Tylenol Targets Pain Through Unexpected Endocannabinoid Pathway

A new study reveals that acetaminophen (Tylenol) relieves pain by reducing levels of an endocannabinoid called 2-AG, rather than increasing it as previously thought. This discovery challenges decades-old assumptions about how pain relief works and may open the door to designing safer, more targeted medications.

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·May 4, 2023·6 min read

Underlying Mechanism of Neuropathic Pain Revealed

The enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord is responsible for initiating and maintaining neuropathic pain. Targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviates pain hypersensitivity.

Featured Neurology Neuroscience Pain

·September 20, 2023·6 min read

Unlocking Non-Opioid Pain Relief: Acetylcholine’s Untapped Potential

Researchers have unveiled a groundbreaking discovery in the field of pain management: an alternative pathway in the brain that provides relief similar to opioids but without the addiction risks. This mechanism leverages the neurotransmitter acetylcholine in the ventrolateral periaqueductal gray (vlPAG) region of the brain.

Featured Neuroscience Pain Psychology

·August 7, 2023·4 min read

Untangling the Ties Between Chronic Pain and Mental Health

A recent commentary underscores the complex relationship between chronic pain and mental health disorders like depression and anxiety. The interaction is revealed to be driven by a bi-directional feedback loop, where physical pain impacts sleep and mood, making individuals more susceptible to mental health issues.

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·March 23, 2020·2 min read

Using cannabinoids to treat acute pain

Meta-analysis of previous studies reveals cannabinoid treatments produce a small, but significant reduction in subjective pain scores for sufferers of chronic pain.

Image shows a baby with the EEG attached to its head.

Featured Neurology Neuroscience Videos Pain

·May 4, 2017·2 min read

Using Simple Brain Scan to Detect Pain in Infants

Researchers have developed an EEG technique that can help monitor pain in infants. The believe the technology could have beneficial applications in testing pain and analgesic efficacy in older non-verbal patients also.