Researchers explore the close relationship between depression and pain. For some people, unexplained symptoms of pain, such as back or headaches, could be an early indicator of depression before mood changes occur.
Discovery could pave the way for new treatments for chronic pain in humans, researchers report.
Duke researchers have discovered head and facial sensory neurons are directly wired into one of the brain's main emotional signaling hubs. Sensory neurons throughout the rest of the body are indirectly connected to the system. The findings help explain why head and face pains are more emotionally draining than other pains.
Researchers identified a distinct population of GABAergic neurons activated by general anesthetic in the central amygdala of mice. The findings point to central amygdala GABAergic neurons as a potential therapeutic target to alleviate chronic pain.
Conolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.
Cannabis terpenes, the part of the plant which provides aroma and flavor, may provide therapeutic benefits in controlling pain, a new study reports.
Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.