Many people who suffer migraines are often diagnosed with other conditions. For those with a clinical diagnosis, many are unaware of treatment options available for pain and to slow the frequency of attacks.
Researchers uncover the mechanism behind how a subset of NSAIDs reduces inflammation, which helps explain some of the curious side effects of the anti-inflammatories.
Core neurons in the lateral parabrachial nucleus project to the amygdala, an area of the brain associated with fear and emotional processing of pain. Neurons in the shell project to the pre-Bötzinger complex, a region that generates breathing rhythm. Both core and shell neurons influence each other according to inputs from each area, increasing breathing rate when we are in pain or anxious.
Classical music exposure paired with ibuprofen reduced response to inflammation pain by 93%, compared to exposure to the medication alone in mouse models of pain. For those exposed to just music, researchers report a 77% reduction in surgical pain.
A number of patients who contracted COVID-19 in the early months of the pandemic reported symptoms of neuropathy, including pain, tingling sensations, and numbness that lasted up to three months after recovery. The findings suggest COVID-19 may have lingering effects on peripheral nerves.