35% of patients who used ketamine to manage pain reported significant side effects ranging from hallucination, out-of-body experiences, visual disturbances, and urinary dysfunction. 20% of the side effects were linked directly to ketamine, and 15% associated with ketamine in combination with other drugs.
Researchers have implicated serotonin in the pathophysiology of RA.
A Western-style diet, high in omega-6 polyunsaturated fats, increases symptoms of inflammation, neuropathy, and chronic pain. However, changing to a lower-fat diet can help reverse or relieve symptoms of inflammatory pain disorders.