Duke researchers have discovered head and facial sensory neurons are directly wired into one of the brain's main emotional signaling hubs. Sensory neurons throughout the rest of the body are indirectly connected to the system. The findings help explain why head and face pains are more emotionally draining than other pains.
Reducing sensitivity to physical pain resulted in a reduction of pain empathy toward others, a study found. The results suggest a possible neurobiological link between pain and empathy.
COVID-19 infection leaves a gene expression signature in the dorsal root ganglia which persist after the virus has cleared. The signature matched other gene expression patterns seen in pain caused by other conditions.
People with osteoarthritis in the knee who report more pain sensations are more likely to suffer constant and unpredictable pain. Researchers identified a potential mechanism in the nervous system that could explain why people experience varying pain patterns associated with knee osteoarthritis.
Widespread pain, a subset of chronic pain associated with musculoskeletal disorders, is linked to an increased risk of all types of dementias, including Alzheimer's disease, and a greater risk of stroke.