Researchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease.
Zolgensma, an FDA approved gene therapy, supplements the production of the SMN protein to improve motor neuron function in children with spinal muscular atrophy after just one dose.
Researchers report they have successfully developed 'mini-brains' made up of the many neurons and cells in the human brain. The mini brains could allow for better research and reduce the need for animal testing.
Researchers establish SCN3A genetic mutations cause infantile epileptic encephalopathy.
Researchers have developed nanowires that can record the electrical activity of neurons in fine detail. The technology will allow for better investigation as to how the brain works.
Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder.
MicroRNA-132 regulates neurogenesis in the hippocampus, according to both mouse and human tissue studies. Restoring levels of microRNA-132 in mouse models of Alzheimer's disease reduces neurogenetic deficits and restores cognitive abilities, researchers say.
Researchers take a deeper look at synesthesia, revealing the condition could be linked to some autoimmune diseases. The paper also reports synesthetes have better memory and are more creative than those without the disorder.