Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 13, 2020·4 min readProtein associated with ovarian cancer exacerbates neurodegeneration in Alzheimer’sOCIAD1, a protein commonly associated with ovarian cancer, contributes to neurodegeneration in Alzheimer's disease by impairing mitochondrial function, leading to synaptic damage and neural vulnerability.Read More
FeaturedGeneticsNeurologyNeurosciencePsychology·January 13, 2020·6 min readWhen pregnant moms are stressed out, babies’ brains sufferStress and anxiety during pregnancy are associated with impaired fetal cerebellar and hippocampal development in children with congenital heart disease.Read More
ElectrophysiologyFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 12, 2020·4 min readNeurons’ energy organelle protected from damage linked to ALS & Alzheimer’sResearchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.Read More
ElectrophysiologyFeaturedGeneticsNeurologyNeuroscience·January 12, 2020·4 min readA molecular switch for repairing central nervous system disordersA global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 12, 2020·3 min readPeering into the genome of brain tumorA new convolutional neural network that utilizes MRI brain scans can forecast genetic mutations in glioma brain tumors.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 10, 2020·2 min readAntibiotics could be promising treatment for form of dementiaGentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia.Read More
ElectrophysiologyFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 9, 2020·4 min readRejuvenating the brain: More stem cells improve learning and memory of old miceCritical aspects of hippocampal function can be reversed in old age, or compensated for throughout life, with the help of neural stem cells.Read More
AutismFeaturedGeneticsNeuroscience·January 9, 2020·3 min readMissing protein in brain causes behaviors mirroring autismp75NTR, a protein implicated in normal brain development and Alzheimer's disease, may play a role in the development of autism. Mice bred without the protein exhibited learning deficits similar to those associated with ASD.Read More
FeaturedGeneticsNeuroscience·January 8, 2020·4 min readAbnormal neuron activity manifests as parental neglectAbnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 7, 2020·4 min readRemoving body clock gene protects mice against pneumoniaRemoving BMAL1, a gene commonly associated with circadian rhythm, makes macrophages more effective and the body more resistant to pneumonia.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 7, 2020·2 min readSmart algorithm finds possible future treatment for childhood cancerUsing big data, researchers have developed a new computer algorithm capable of analyzing genetic and pharmacological information to suggest new treatment options for neuroblastoma.Read More
FeaturedGeneticsNeuroscience·January 7, 2020·3 min readCancer-like metabolism makes brain growThe ARHGAP11B protein located in mitochondria induces a metabolic pathway, similar to the characteristics of cancer cells, in brain stem cells, resulting in brain development.Read More