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Genetics

Genetics articles related to neuroscience research will be listed here.

Featured Genetics Neurology Neuroscience

·December 4, 2023·4 min read

The Role of Protein Misfolding in Neurodegenerative Diseases

Neurodegenerative diseases share a common factor: protein misfolding and deposits in the brain. Misfolded proteins can lead to toxic activity or the loss of the protein's physiological function, causing damage to neurons.

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Featured Genetics Neuroscience Psychology

·December 1, 2023·4 min read

Peptide PACAP’s Key Role in Alcohol Addiction

Alcohol, the world's most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers discovered a key player in alcohol addiction: pituitary adenylate cyclase activating polypeptide (PACAP).

Featured Genetics Neuroscience Psychology

·November 30, 2023·5 min read

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

Researchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes.

Featured Genetics Neuroscience

·November 28, 2023·5 min read

Protein Key to Lifespan and Healthy Aging Identified

A new study reveals the significant role of the CD300f immune receptor in determining life expectancy and healthy aging in mice. The absence of this protein in immune system cells, particularly in macrophages and microglia, leads to shorter life spans and pathologies related to cognitive decline and premature aging, with a more pronounced effect in females.

Featured Genetics Neuroscience

·November 28, 2023·5 min read

Unlocking Genes Behind Neurodevelopmental Disorders

Researchers made a significant breakthrough in understanding neurodevelopmental disorders by identifying how three novel genes contribute to these conditions. The study utilized genomic sequencing, phenotyping, and modeling in fly and stem cells to investigate the genetic architecture of these genes. They discovered that malfunctions in the spliceosome, a protein complex responsible for gene splicing, are a key factor in these disorders.

Featured Genetics Neurology Neuroscience

·November 27, 2023·6 min read

Pioneering Stem Cell Therapy for Progressive Multiple Sclerosis Shows Promise

An international team has conducted a groundbreaking study on stem cell therapy for progressive multiple sclerosis (MS). The therapy, involving the injection of neural stem cells into patients' brains, was found to be safe and potentially effective in preventing further brain damage.

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Featured Genetics Neuroscience

·November 21, 2023·4 min read

Genetic Links in Cannabis Use Disorder

Researchers analyzed over 1 million genomes, revealing insights into cannabis use disorder and its ties to psychiatric issues, other substance abuses, and lung cancer risks. The study, part of the Million Veteran Program, identified genetic variants linked to cannabis use disorder and its associated health and behavioral problems.

Featured Genetics Neurology Neuroscience

·November 16, 2023·6 min read

Mutation in Brain’s Immune Cells Linked to Alzheimer’s Risk

A genetic mutation affecting microglia, the brain's immune cells, can increase the risk of Alzheimer's disease up to threefold. The mutation, known as TREM2 R47H/+, impairs microglia function and contributes to Alzheimer's pathology.

Featured Genetics Neuroscience

·November 13, 2023·5 min read

Childhood Stress Has A Greater Genetic Impact Than Brain Injury

Researchers discovered that early-life stress alters more brain genes than childhood head injuries, as shown in a rat study. This research used a rat model to mimic human early-life stress and head injury, revealing significant genetic changes in the hippocampal region.

Autism Featured Genetics Neuroscience

·November 9, 2023·6 min read

Autism Gene SYNGAP1’s Early Role in Brain Development

A new study uncovers unexpected early developmental impacts of SYNGAP1 gene variants linked to Autism Spectrum Disorder. By examining brain organoids, including those from a patient with a SYNGAP1 variant, researchers found the SYNGAP1 protein in progenitor cells, challenging the belief that it's only present in mature neuron synapses.

Featured Genetics Neuroscience

·November 9, 2023·4 min read

Slumber’s Fountain: The Sleep-Aging DNA Connection

New research explores how sleep disturbances might accelerate aging by affecting DNA methylation, a chemical modification in our DNA. Using the jewel wasp as a model, scientists will examine the link between sleep deprivation and biological aging markers.

Featured Genetics Neuroscience

·November 8, 2023·2 min read

Childhood Slumber Shadows: Genetics Link to Sleep Quality

New research reveals that genetic variants influencing sleep patterns in adults also affect children's sleep quality and duration. Analyzing data from 2,458 children, the study found that those with a genetic predisposition for insomnia experienced more sleep disturbances, while those inclined towards longer sleep faced frequent night awakenings.

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Genetics

The Role of Protein Misfolding in Neurodegenerative Diseases

Peptide PACAP’s Key Role in Alcohol Addiction

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

Protein Key to Lifespan and Healthy Aging Identified

Unlocking Genes Behind Neurodevelopmental Disorders

Pioneering Stem Cell Therapy for Progressive Multiple Sclerosis Shows Promise

Genetic Links in Cannabis Use Disorder

Mutation in Brain’s Immune Cells Linked to Alzheimer’s Risk

Childhood Stress Has A Greater Genetic Impact Than Brain Injury

Autism Gene SYNGAP1’s Early Role in Brain Development

Slumber’s Fountain: The Sleep-Aging DNA Connection

Childhood Slumber Shadows: Genetics Link to Sleep Quality

100,000 Small Factors Rival DNA in Disease Risk

The Brain Stacks Sound Information to Navigate the Dark

Edge of Chaos: Why Pigeons Refuse to Become “Machines”

Brain’s Default Setting for Ambiguity Matters for Mental Health

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