Study reports that age-related loss of the Y chromosome in men is linked to heart muscle scarring and an increased risk of heart failure. The findings may explain why men tend to die, on average, seven years younger than women.
A new study reveals a genetic link between Alzheimer's disease and several gut-related disorders. Researchers report Alzheimer's patients and those with intestinal disorders have specific genes in common. The findings add to the evidence the gut-brain axis may play a role in the development of neurodegenerative disorders.
Researchers have created a new blueprint that outlines how embryonic stem cells from mice become sensory interneurons and identified a method for producing sensory interneurons in a lab setting. If the results can be replicated in human stem cells, researchers say the findings could contribute to the development of therapies to restore sensation to those suffering nerve damage and spinal cord injury.
In males, sun exposure activates the p53 protein which signals to the body to produce the appetite-associated ghrelin hormone. In women, estrogen blocks the interaction between p53 and ghrelin, reducing the urge to eat following sun exposure.
Genes associated with alcohol and smoking addiction are over-represented in specific neurons, a new study reports. Researchers found genes associated with smoking were also linked to pain perception and food response while genes linked to alcohol addiction were associated with stress and learning.
Researchers have identified a set of genetic mutations that protect against cognitive decline in older adults. A new study suggests the selective pressure from infectious pathogens like gonorrhea may have promoted the emergence of this genetic variance in Homo sapiens.
Researchers discovered how the TGF-beta protein controls the process by which hair follicles, including stem cells, divide and form new cells or orchestrate apoptosis. The findings could provide new treatment options for baldness and therapies to speed up wound healing.
In cognitively healthy people with a genetic risk for Alzheimer's, retinal changes have been associated with alterations in the entorhinal cortex, hippocampus, and lingual gyrus. Researchers say retinal changes can be used to track changes in brain structures associated with Alzheimer's in those with genetic risk factors.
Members of the British military who witnessed nuclear test programs in the 1950s and 60s are no more likely to pass on genetic alterations to their offspring and future generations than other members of the military, a new study reports.
The discovery of new genetic signatures associated with age-related macular degeneration may lead to better diagnosis and treatment of the currently incurable vision disorder.