Infiltrating gliomas are shaped by their genetic evolution and microenvironment, researchers report. The findings may help in the development of therapies to treat glioma brain tumors.
A new protocol for differentiating human embryonic stem cells to RPE cells could be a safe and effective approach for treating age-related macular degeneration.
Taste-related genes may play a significant role in determining personal food and diet choices, and could also have an impact on cardiometabolic health.
Study reveals the mechanism by which genes coding for a subset of long non-coding RNA interacts with neighboring genes to regulate the development and function of cortical neurons.
Researchers developed a new method for producing high numbers of human photoreceptor cells. The human photoreceptor cells can be transplanted in bulk to partially degenerated mouse retinas and improve the detection of daylight in mice with damaged eyesight.
Study reveals how neurons and glial cells contribute to drive neurodegeneration following brain injury.
The absence of the NCX3 gene amplifies pain signals within the spinal cord, a new mouse study reveals. Increasing levels of NCX3 in the spinal cord helped reduce symptoms associated with chronic pain.
Researchers have identified a molecule in the blood that is produced during exercise. The molecule, Lac-Phe, can effectively reduce food intake and obesity in mouse models.
Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.
Study identifies a specific protein in sensory neurons that detects mechanical itch stimuli such as an insect crawling on the skin or when one touches an object that irritates the skin.
Maternal autoantibody–related autism spectrum disorder (MAR ASD) is marked by specific maternal antibodies that react to certain proteins in the fetal brain. Examining the plasma of expecting mothers, researchers found mothers with reactivity to one of the nine MAR ASD patterns were eight times as likely to have a child diagnosed with autism.
Researchers identified three different MINAR2 genetic mutations that were responsible for deafness in 13 people from four different families.
