Researchers have identified a mechanism shared by mutations in the SHANK3 and ADNP genes. The genes have been associated with the development of ASD and schizophrenia.
From keeping active and eating a healthy diet to controlling cholesterol and reducing sugar intake, researchers report on seven simple lifestyle changes older adults with genetic risk factors can make to reduce the chance of developing dementia.
The FMNL2 gene links cerebrovascular disease and Alzheimer's disease, a new study reports. Changes of activity in the FMNL2 caused by cerebrovascular disease prevent the efficient cleaning of toxic proteins in the brain, leading to the development of Alzheimer's disease.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.