Neuroscience research published in September's Journal of Neuroscience suggests early life stresses may modify the GAD1 gene, which controls the production of GABA. Through their research on rats, researchers were able to note that those who experienced a lack of affection showed an obstruction within the DNA which controls the GAD1 gene. As it is believed that GABA deficits might be apparent within schizophrenic patients, researchers propose that the modification of GAD1 might determine a child's predisposition to mental illness.
Researchers genetically altered mesenchymal stem cells to create new stem cell lines that showed no signs of aging in culture, did not increase tumor production in animal studies and functioned as healthy mesenchymal cells do.
Two healthy baby girls and a healthy baby boy were born recently after genetic screening study. These babies were the first human babies born that relied on IVF and had each chromosome assessed in each oocyte before IVF. The genetic screening technique used improves on many other methods.
Neurobiologists have genetically engineered mice to smell light. This optogenetics research provides a better understanding of the neural basis of...
Zif proteins have been found to control whether a brain stem cell differentiates into a neuron or renews as a brain stem cell. There are Zif related proteins in humans that may be targeted by new treatments for brain cancer and other diseases.
The removal of a certain class of potassium channels from the surface of nociceptors is believed to be a key factor in inflammatory pain signaling. Using gene interference to reduce the expression of these specific potassium channels on nociceptors, researchers were able to produce hyperexcitability in nociceptors resembling that seen in inflammatory pain signaling.
After inserting a gene into mice that increases choline transporter and as a result increases acetylcholine at the neuromuscular junctions, the engineered mice were able to run on treadmills twice as long as controls without the inserted gene.
Huntington’s disease research using simple organisms such as baker’s yeast has yielded new information about underlying mechanisms of Huntington’s disease...
The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."