Immune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. These immune cells help to guard the brain and spinal cord against inflammation and infection.
Gantenerumab, an investigational drug for Alzheimer's disease, reduced amyloid plaques and lowered tau levels in the brains of people with genetic risk factors for the neurodegenerative disorder.
A study spanning 17 years has found children born and raised in poverty had smaller subcortical brain regions, including the hippocampus, caudate, putamen, and thalamus. These brain areas also showed less growth over time.
A new study reports a strong association between high levels of physical activity and the ability to maintain cognitive function in breast cancer patients who received chemotherapy.
Chikungunya, and other mosquito-borne alphaviruses are known to trigger brain infections and arthritis in those who contract the infections. Researchers have identified two antibodies that protect animals from diseases caused by alphaviruses. The findings could pave the way to new treatments and a universal vaccine for alphaviruses.
Researchers have identified a new reward system in the brain. The study found long-range GABA neurons from the ventral tegmental area to the ventral nucleus accumbens shell are engaged in reward and reinforcement behaviors. This GABAergic projection inhibits cholinergic interneurons.
A new algorithm uses neuroimaging data of amyloid levels in the brain and takes into account a person's age to determine when a person with genetic Alzheimer's risk factors, and with no signs of cognitive decline, will develop the disease.
Daily release of glucocorticoids depends on coordination between the clock gene and activity rhythms of neurons within two parts of the hypothalamus.