Weill Cornell Medicine researchers may have answered why women are more likely to develop Alzheimer's disease than men. In a new PLOS ONE study, researchers reveal menopause can cause metabolic changes in the brain that appear to increase the risk of Alzheimer's disease.
A new study reports sensory stimulation during the first two weeks of life is critical for establishing brain networks that help map sensation.
Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems.
Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.
A specific group of fungi in the intestines may protect against intestinal injury and influence social behaviors.
Tau-tangles trigger the inflammatory activation of microglia via the NF-κB pathway. Inhibiting the microglia NF-κB signaling pulled the immune cells out of their inflammatory state and reversed learning and memory problems in tau-based Alzheimer's mouse models.