Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.
A new study reports sensory stimulation during the first two weeks of life is critical for establishing brain networks that help map sensation.
Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems.
Researchers reveal high salt intake reduces resting cerebral blood flow and can contribute to dementia in mice.
FOXO3, a gene linked to longevity in humans, protects neural stem cells from the negative effects of stress.
Tau-tangles trigger the inflammatory activation of microglia via the NF-κB pathway. Inhibiting the microglia NF-κB signaling pulled the immune cells out of their inflammatory state and reversed learning and memory problems in tau-based Alzheimer's mouse models.
Weill Cornell Medicine researchers may have answered why women are more likely to develop Alzheimer's disease than men. In a new PLOS ONE study, researchers reveal menopause can cause metabolic changes in the brain that appear to increase the risk of Alzheimer's disease.
A specific group of fungi in the intestines may protect against intestinal injury and influence social behaviors.
A variant of the FAAH gene increases vulnerability to THC in females and has a larger-scale impact on brain regions responsible for reward processing.
